Gene Mapping in the Pig

Fries, R.; Vögeli, P.; Stranzinger, G.

doi:10.1016/b978-0-12-039234-6.50015-x

Cited by 9 publications

(7 citation statements)

References 193 publications

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“…The details on the preparation of anti-IGH reagents and IGH allotyping of individual serum samples using immunodiffusion or immunoelectrophoresis in agar gels have been described by Rapacz & Hasler-Rapacz (1982). In this study only the IGHGl locus (designation according to Vogeli et al 1987;Fries et al 1990) with the allelic allotypes designated IGHGl A1 and IGHG1 A2 is considered.…”

Section: Igh Allotypesmentioning

confidence: 99%

“…Relative to the advanced knowledge of the order and chromosomal location of gene loci in man and some laboratory animal species, little is known about the porcine gene map. The present gene map of swine consists of six linkage groups (detected by family analyses) and four syntenic groups (detected by somatic cell hybridization techniques) (Fries et al 1990). The present contribution to the swine gene map was obtained when the linkage relationships of several immunogenetic and biochemical markers and enterocyte receptor phenotypes were analysed by the lod score method.…”

Section: Introductionmentioning

confidence: 99%

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Evidence for linkage between the swine L blood group and the loci specifying the receptors mediating adhesion of K88 Escherichia coli pilus antigens

et al. 1992

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Brush borders or enterocytes obtained from the small intestine of 248 pedigreed pigs were tested by adhesion assay in vitro with enterotoxigenic Escherichia (E.). coli strains, each expressing one of the three K88 pilus variants K88ab, K88ac and K88ad. All pigs were classified as belonging to one of the four adhesion phenotypes: I ‐ K88ab(‐), ac(‐), ad(‐); II‐K88ab(‐), ac(‐), ad(+); III‐K88ab(+), ac(+), ad(‐); and IV‐K88ab(+), ac(+), ad(+). Serum or red cells were typed for 15 blood group systems: A‐O, B, C, D, E, F, G, H, I, J, K, L, M, N and O; for 11 biochemical polymorphisms: PI1, PI2, PO1A, A1BG, GPI, PGD, TF, HPX, ADA, PGM and AMY; the polymorphism at the IGHG1 locus. Linkage analysis was performed between the alleles at the locus (loci) specifying K88 receptors able to bind one or more different serological types of K88 E. coli and alleles for markers at other loci. Linkage was demonstrated between the locus for the L blood group system and the locus (loci) for K88 E. coli receptors (Ẑ= 3.24), adding one locus (loci) to the previously identified linkage group IV (LGIV) [L‐SLB]. The maximum likelihood estimate of the recombination fraction (0C) was 0.23. No evidence was found for linkage between any of the other biochemical and immunogenetic markers and the receptor locus (loci) of K88 E. coli.

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Section: Igh Allotypesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evidence for linkage between the swine L blood group and the loci specifying the receptors mediating adhesion of K88 Escherichia coli pilus antigens

et al. 1992

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“…The SLA complex maps to the p12-q12 region of pig chromosome 7 (Fries et al, 1990). The genomic organization of the SLA region is in the order class II-class III-class I, similar to that of the human and bovine MHC region (Xu et al, 1992).…”

Section: Introductionmentioning

confidence: 98%

Genetic Variation of Exon 2 of SLA-DQB Gene In Chinese Pigs

Fang

Braunschweig

et al. 2005

Biochem Genet

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A 273 base pair (bp) fragment of the SLA-DQB gene including parts of intron 1 and exon 2 has been investigated using PCR-RFLP in 38 indigenous Chinese pig breeds, two Chinese wild boars, and three foreign pig breeds. The restriction enzyme RsaI revealed three polymorphic sites in the 273 bp fragment for the pig breeds studied. In total, four alleles resulting in 10 genotypes were found. Twenty pig breeds are not in Hardy-Weinberg equilibrium at this locus. The allele frequency of a chi-square test showed that there is significant difference (P < 0.05) among six Chinese pig groups, and an even greater significant difference (P < 0.01) was found between Chinese and European pig breeds.

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“…The present gene map of swine consists of six linkage groups (detected by family analyses) and four syntenic groups (detected by somatic cell hybridization techniques) (Fries et al 1990). The present gene map of swine consists of six linkage groups (detected by family analyses) and four syntenic groups (detected by somatic cell hybridization techniques) (Fries et al 1990).…”

Section: Introductionmentioning

confidence: 99%

Evidence for linkage between the swine L blood group and the loci specifying the receptors mediating adhesion of K88 Escherichia coli pilus antigens

et al. 1992

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Summary. Brush borders or enterocytes obtained from the small intestine of 248 pedigreed pigs were tested by adhesion assay in vitro with enterotoxigenic Escherichia (E.). coli strains, each expressing one of the three K88 pilus variants K88ab, K88ac and K88ad. All pigs were classified as belonging to one of the four adhesion phenotypes: I ‐ K88ab(‐), ac(‐), ad(‐); II‐K88ab(‐), ac(‐), ad(+); III‐K88ab(+), ac(+), ad(‐); and IV‐K88ab(+), ac(+), ad(+). Serum or red cells were typed for 15 blood group systems: A‐O, B, C, D, E, F, G, H, I, J, K, L, M, N and O; for 11 biochemical polymorphisms: PI1, PI2, PO1A, A1BG, GPI, PGD, TF, HPX, ADA, PGM and AMY; the polymorphism at the IGHG1 locus. Linkage analysis was performed between the alleles at the locus (loci) specifying K88 receptors able to bind one or more different serological types of K88 E. coli and alleles for markers at other loci. Linkage was demonstrated between the locus for the L blood group system and the locus (loci) for K88 E. coli receptors (Ẑ= 3.24), adding one locus (loci) to the previously identified linkage group IV (LGIV) [L‐SLB]. The maximum likelihood estimate of the recombination fraction (0C) was 0.23. No evidence was found for linkage between any of the other biochemical and immunogenetic markers and the receptor locus (loci) of K88 E. coli.

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Gene Mapping in the Pig

Cited by 9 publications

References 193 publications

Evidence for linkage between the swine L blood group and the loci specifying the receptors mediating adhesion of K88 Escherichia coli pilus antigens

Evidence for linkage between the swine L blood group and the loci specifying the receptors mediating adhesion of K88 Escherichia coli pilus antigens

Genetic Variation of Exon 2 of SLA-DQB Gene In Chinese Pigs

Evidence for linkage between the swine L blood group and the loci specifying the receptors mediating adhesion of K88 Escherichia coli pilus antigens

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