Gene frequencies of ABO and Rh blood groups in Nigeria: A review

Anifowoshe, Abass Toba; Owolodun, Olubukola Abibat; Akinseye, Kehinde Monica; Iyiola, Oluyinka A.; Oyeyemi, Bolaji Fatai

doi:10.1016/j.ejmhg.2016.10.004

Cited by 30 publications

(36 citation statements)

References 34 publications

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“…The distribution of Rh blood group is also known to vary among different populations, nevertheless, Rh + has been found to be highly predominant compared to Rh -. The pattern observed in our study (Rh + ˃Rh -: 95.6%, 4.4%) is generally consistent with previous studies within Nigeria [3,13,[16][17][18][19][20][21][22] , while we reported a value of 4.4% prevalence for Rh -in our study, other studies reported values as low as 2.9% in Yola, Nigeria [18] , 2.3% in Uganda [14] and 1.2%…”

Section: Resultssupporting

confidence: 77%

“…A study conducted in Lagos, Nigeria [22] reported the prevalence of groups O, A, B and AB as 51.8%, 26.3%, 18.2% and 3.6% respectively. One nation-wide study [3] , reported similar pattern of ABO distribution (O>A>B>AB: 52.93%, 22.77%, 20.64% and 3.66% respectively). Likewise, similar studies conducted among African students in Port Harcourt [23] , Niger Delta area [24] and Benin City area of South-South, Nigeria [20] reported values similar to our findings.…”

Section: Resultsmentioning

confidence: 64%

“…(Table 3). [2,3,[18][19][20][21][22] . A study conducted in Lagos, Nigeria [22] reported the prevalence of groups O, A, B and AB as 51.8%, 26.3%, 18.2% and 3.6% respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Individuals who lack the Rh-D antigen produce anti-Rh-D antibodies when they encounter the D-antigen on transfused red blood cells (RBC), Rh-D incompatibility could result in serious haemolytic transfusion reaction (HTR) and hemolytic disease of the newborn (HDN) [3,10] The importance of the ABO and Rh blood group systems in transfusion science cannot be over emphasized as the major components of grouping and cross-matching is to ensure compatibility of the ABO and Rh blood group to avoid transfusion of incompatible blood which can result in transfusion reactions. Hence, in transfusion science, every blood must be screened for ABO and Rh compatibilities before transfusion [11,12] .…”

Section: Research Articlementioning

confidence: 99%

“…individual's RBCs determines the particular blood group system [3] , the ABH antigens are oligosaccharides in nature and the H antigen is a precursor substance that is converted to either A or B antigen (or both) by specific glycosyltranferases encoded by the ABO gene located on chromosome 9 [4,5] .…”

Section: Introductionmentioning

confidence: 99%

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Gene Frequencies of Haemoglobin Genotype, ABO and Rhesus Blood Groups among Students Population of a Private University in Nigeria-Implications for Blood Banking

Ohiengbomwan¹,

Idemudia²,

Owoicho³

et al. 2018

IJLSSR

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Background-ABO and Rhesus blood groups are the two most important blood group systems of clinical significance, ABO is classified into four major groups (A, B, AB and O) while Rhesus is classified as positive or negative. Haemoglobin genotype includes both normal (HbA) and the variant forms (HbS and HbC) which combine to form six major haemoglobin gene types (HbAA, HbAS, HbAC, HbCC, HbSS, and HbSC). Several studies have determined the gene frequencies of haemoglobin genotype, ABO and Rhesus blood groups among different populations with varied patterns. This study is aimed at assessing the gene frequencies of haemoglobin genotype, ABO and Rhesus blood groups among Redeemer's University students. Methods-This study was a retrospective study which analyzed laboratory data between 2013 and 2017 containing haemoglobin genotype and Rhesus-ABO investigations carried out for newly admitted students. Results-The ABO gene frequencies from this study showed O˃A˃B˃AB; 59.7%, 21.6%, 16.6% and 2.0%, ABO with Rhesus combination showed O + ˃A + ˃B + ˃O -˃AB + ˃A -˃B -˃AB -; 57.1%, 20.8%, 15.9%, 2.6%, 1.8%, 0.8%, 0.7%, and 0.3%. Rhesus positive was found to be far higher than Rhesus negative (Rh + ˃Rh -; 95.6%, 4.4%) and haemoglobin genotype distribution showed HbAA˃HbAS˃HbAC˃HbSS˃HbSC˃HbCC; 72.5%, 23.4%, 2.4%, 1.5%, 0.2% and 0.1%. Conclusion-Blood group O, Rhesus positive and haemoglobin AA were found to be more prevalent all through the period under review.

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Section: Resultssupporting

confidence: 77%

Section: Resultsmentioning

confidence: 64%

“…(Table 3). [2,3,[18][19][20][21][22] . A study conducted in Lagos, Nigeria [22] reported the prevalence of groups O, A, B and AB as 51.8%, 26.3%, 18.2% and 3.6% respectively.…”

Section: Resultsmentioning

confidence: 99%

Section: Research Articlementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Gene Frequencies of Haemoglobin Genotype, ABO and Rhesus Blood Groups among Students Population of a Private University in Nigeria-Implications for Blood Banking

Ohiengbomwan¹,

Idemudia²,

Owoicho³

et al. 2018

IJLSSR

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High prevalence of serological weak D phenotype and preponderance of weak D type 4.0.1. genetic variant in a Nigerian population: implications for transfusion practice in a resource-limited setting

Maryam

Mukhtar

Yusuf

et al. 2022

Hematology, Transfusion and Cell Therapy

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ABO blood group as a risk factor for tuberculosis: A network meta-analysis

Hao

Horita

Matsumoto

et al. 2021

International Journal of Infectious Diseases

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Background: Despite numerous studies on ABO blood group and risk of tuberculosis, no consensus has been reached. Methods: We conducted a systematic review following the Meta-Analysis of Observational Studies in Epidemiology group statement. English language articles providing odds ratio data regarding tuberculosis risk among ABO groups were eligible. Least-squares approach random-model network and random-model pairwise meta-analyses were conducted. The protocol-specified primary outcome was tuberculosis risk among ABO groups in the form of odds ratios calculated via a network metaanalysis. Results: We identified 28 studies with 30 populations comprising 15,664 patients with tuberculosis and 254,610 controls. Subjects with AB blood type had a higher risk of becoming infected with tuberculosis than those with blood type O (odds ratio (OR) = 1.26, 95% confidence interval (CI): 1.14-1.38), A (OR = 1.25, 95% CI: 1.14-1.38), and B (OR = 1.22, 95% CI: 1.11-1.34). Pairwise comparison revealed that AB blood type was a risk factor for tuberculosis with OR = 1.23 (95% CI: 1.02-1.48) compared to other blood types. Region-based subgroup analyses suggested that the AB blood group was a substantial risk in Africa (OR = 1.78, 95% CI: 1.39-2.28) and India (OR = 1.48, 95% CI: 1.14-1.92). Conclusions: AB blood group is a risk factor for tuberculosis of a substantial magnitude in Africa and India.

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Gene frequencies of ABO and Rh blood groups in Nigeria: A review

Cited by 30 publications

References 34 publications

Gene Frequencies of Haemoglobin Genotype, ABO and Rhesus Blood Groups among Students Population of a Private University in Nigeria-Implications for Blood Banking

Gene Frequencies of Haemoglobin Genotype, ABO and Rhesus Blood Groups among Students Population of a Private University in Nigeria-Implications for Blood Banking

High prevalence of serological weak D phenotype and preponderance of weak D type 4.0.1. genetic variant in a Nigerian population: implications for transfusion practice in a resource-limited setting

ABO blood group as a risk factor for tuberculosis: A network meta-analysis

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