Gene Expression Studies in Down Syndrome; What Do They Tell Us about Disease Phenotypes?
Laura Rebecca Chapman,
Isabela Ramnarine,
Dan Zamke
et al.
Abstract:Background: Down Syndrome is the most well-studied aneuploidy condition in humans. It is associated with multiple disease phenotypes including cardiovascular, neurological, haemato-logical, and immunological disease processes. In this review paper we aim to discuss the research into gene expression studies performed at the fetal stage of development. Methods: A descriptive review was performed including all papers published on the PubMed database between Septem-ber 1960- September 2022. Results: In the amnioti… Show more
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