Gene expression signatures of response to fluoxetine treatment: systematic review and meta-analyses
David G. Cooper,
J. Paige Cowden,
Parker A. Stanley
et al.
Abstract:BackgroundSelecting the best antidepressant for a patient with major depressive disorder (MDD) remains a challenge, and some have turned to genomic (and other ‘omic) data to identify an optimal therapy. In this work, we synthesized gene expression data for fluoxetine treatment in both human patients and rodent models, to better understand biological pathways affected by treatment, as well as those that may distinguish clinical or behavioral response.MethodsFollowing the PRISMA guidelines, we searched the Gene … Show more
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