2012
DOI: 10.1186/1471-213x-12-13
|View full text |Cite
|
Sign up to set email alerts
|

Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds – indications of prenatal initiation of postnatal phenotypic differences

Abstract: BackgroundThe mammary gland is key to all mammal species; in particular in multiparous species like pigs the number and the shape of functional mammary gland complexes are major determinants of fitness. Accordingly, we aimed to catalog the genes relevant to mammogenesis in pigs. Moreover, we aimed to address the hypothesis that the extent and timing of proliferation, differentiation, and maturation proccesses during prenatal development contribute to postnatal numerical, morphological and functional properties… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
8
0

Year Published

2015
2015
2018
2018

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 6 publications
(9 citation statements)
references
References 53 publications
1
8
0
Order By: Relevance
“…In multiparous pigs, the number and the shape of functional mammary gland complexes are major determinants of the mothering ability of sows. Sow milk yield and quality is crucial for the survival and growth of piglets [ 16 ]. The mammary gland prepares for lactation by undergoing extensive growth and differentiation during pregnancy.…”
Section: Discussionmentioning
confidence: 99%
“…In multiparous pigs, the number and the shape of functional mammary gland complexes are major determinants of the mothering ability of sows. Sow milk yield and quality is crucial for the survival and growth of piglets [ 16 ]. The mammary gland prepares for lactation by undergoing extensive growth and differentiation during pregnancy.…”
Section: Discussionmentioning
confidence: 99%
“…hNSSCs were isolated and cultured in accordance with our previously published protocols [ 6 , 8 ]. In brief, cells were isolated by explant organ culture to establish outgrowth cell culture ( Figure 1(a) ).…”
Section: Methodsmentioning
confidence: 99%
“…In our previous study, hNSSCs were shown to express thirty-three CD markers including known stromal cell-associated as well as several novel markers [ 6 ]. Moreover, these cells could be induced to differentiate into cells expressing endothelial markers and to form densely packed large diameter tubules during in vitro angiogenesis assay [ 5 , 8 ]. However, the angiogenic capacity of hNSSCs ex vivo remains unclear.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Moreover, RAPGEF1 was also found to be a differentially expressed gene relevant to mammogenesis in pigs during fetal bud formation (Chomwisarutkun et al . ). Thus, we inferred that the SSC5:60296617 SNP may affect teat number by regulating the interaction of EPS8 and RAPGEF1 and, finally, affecting the mammogenesis of pigs.…”
Section: Effect Of the Ssc5:60296617 Snp On Teat Number Traitsmentioning
confidence: 97%