Gene–environment interaction in anorexia nervosa: relevance of non-shared environment and the serotonin transporter gene

Abstract

relationship: depression and stress may promote unhealthy dietary preference, 9 whereas in turn a healthy diet may lower the risk of incident depression over time. 10 The findings of our study provide empirical support to Kiecolt-Glaser's hypothesis 1 about the joint contribution of depression and diet to inflammation, and suggest that intervention aimed at improving the quality of diet may be especially effective in buffering the inflammatory process boosted by depression, which ultimately could result in various health benefits.

5-HTTLPR polymorphism in bulimia nervosa

“…The S-containing genotype interacts significantly with environmental influences, such as high parental control, in conferring a risk for EDs (Uher and McGuffin, 2008;Karwautz et al, 2011), and further research is required to account for …”

Advances in the neurobiology of eating disorders

“…Siblings with the short form of the serotonin transporter were more susceptible to developing anorexia nervosa following early difficulties within the parenting domain [27]. Further studies in the general population have also found interactions between the lower expressing allele of the serotonin transporter and markers of environmental adversity (e.g.…”

Moving to establish the mechanisms underpinning the biopsychiatric models of eating disorders with brain-based translational treatments: from paradigm clash to paradigm complementarity

“…(Karwautz et al, 2011; the parenting domain included parental criticism, high expectations, over/under involvement, minimal affection, control and distress from low parental contact, separation from parents, parental arguments, family conflict avoidance and family social isolation). Further studies in general populations have also found interactions between the lower expressing allele of the serotonin transporter and markers of environmental adversity (e.g.…”