Gene deployment for tooth replacement in the rainbow trout (<i>Oncorhynchus mykiss</i>): a developmental model for evolution of the osteichthyan dentition

Fraser, Gareth J.; Berkovitz, Β.Κ.B.; Graham, Anthony; Smith, Moya Meredith

doi:10.1111/j.1525-142x.2006.00118.x

Cited by 74 publications

(103 citation statements)

References 39 publications

(73 reference statements)

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“…Histological sections revealed that both Shh and Pitx2 were expressed in epithelial cells (Fig. 5 D and E), similar to the epithelial expression of these two genes in developing teeth in mice and other fish species (19,(23)(24)(25)(26). In contrast, Bmp6 expression was dynamically detected in odontogenic epithelial and mesenchymal cells (Fig.…”

Section: Bone Morphogenetic Protein 6 Maps Within the Major-effect Qtlsupporting

confidence: 60%

Evolved tooth gain in sticklebacks is associated with acis-regulatory allele ofBmp6

Cleves

Ellis

Jimenez

et al. 2014

Proc. Natl. Acad. Sci. U.S.A.

147

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Significance How body pattern evolves in nature remains largely unknown. Although recent progress has been made on the molecular basis of losing morphological features during adaptation to new environments (regressive evolution), there are few well worked out examples of how morphological features may be gained in natural species (constructive evolution). Here we use genetic crosses to study how threespine stickleback fish have increased their tooth number in a new freshwater environment. Genetic mapping and gene expression experiments suggest regulatory changes have occurred in the gene for a bone morphogenetic signaling molecule, leading to increased expression in the freshwater fish that have more teeth. Our studies suggest that changes in gene regulation may underlie both gain and loss traits during vertebrate evolution.

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Section: Bone Morphogenetic Protein 6 Maps Within the Major-effect Qtlsupporting

confidence: 60%

Evolved tooth gain in sticklebacks is associated with acis-regulatory allele ofBmp6

Cleves

Ellis

Jimenez

et al. 2014

Proc. Natl. Acad. Sci. U.S.A.

147

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“…3) appear to develop entirely within the surface epithelial layer rather than through invagination of the entire tooth germ. This invaginated dental epithelium is considered essential for tooth replacement in all other known vertebrate dentitions (17,21,32,33). The first-generation parasymphyseal tooth germs in Monotrete spp., which also begin their development in a superficial position, later invaginate deep into the underlying mesenchyme.…”

Section: Resultsmentioning

confidence: 99%

Replacing the first-generation dentition in pufferfish with a unique beak

Fraser

Britz

Hall

et al. 2012

Proc. Natl. Acad. Sci. U.S.A.

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Teleost fishes comprise approximately half of all living vertebrates. The extreme range of diversity in teleosts is remarkable, especially, extensive morphological variation in their jaws and dentition. Some of the most unusual dentitions are found among members of the highly derived teleost order Tetraodontiformes, which includes triggerfishes, boxfishes, ocean sunfishes, and pufferfishes. Adult pufferfishes (Tetraodontidae) exhibit a distinctive parrot-like beaked jaw, forming a cutting edge, unlike in any other group of teleosts. Here we show that despite novelty in the structure and development of this "beak," it is initiated by formation of separate first-generation teeth that line the embryonic pufferfish jaw, with timing of development and gene expression patterns conserved from the last common ancestor of osteichthyans. Most of these first-generation larval teeth are lost in development. Continuous tooth replacement proceeds in only four parasymphyseal teeth, as sequentially stacked, multigenerational, jaw-length dentine bands, before development of the functional beak. These data suggest that dental novelties, such as the pufferfish beak, can develop later in ontogeny through modified continuous tooth addition and replacement. We conclude that even highly derived morphological structures like the pufferfish beak form via a conserved developmental bauplan capable of modification during ontogeny by subtle respecification of the developmental module.evolutionary developmental biology | morphological novelty | tooth development | replacement dentition | phenotypic diversity

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“…2), meaning that each tooth position is replaced with another single tooth in a cyclical manner throughout life [33,34]. The rainbow trout (Oncorhynchus mykiss; Salmonidae) is a relatively basal member of the teleosts and undergoes tooth replacement without a classic dental lamina [33].…”

Section: Osteichthyans (Bony Fishes)mentioning

confidence: 99%

“…The source of epithelial cells necessary for replacing teeth, in most toothed vertebrates, appears to be the dental lamina [10,12,14,28,30,33,46,57,62]. The early odontogenic band provides genetic cues that support a dental fate and the patterning of tooth units from these epithelial cells.…”

Section: The Dental Lamina As a Conserved Feature Of Replacement Dentmentioning

confidence: 99%

Evolution and developmental diversity of tooth regeneration

Tucker

Fraser

2014

Seminars in Cell & Developmental Biology

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127

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a b s t r a c tThis review considers the diversity observed during both the development and evolution of tooth replacement throughout the vertebrates in a phylogenetic framework from basal extant chondrichthyan fish and more derived teleost fish to mammals. We illustrate the conservation of the tooth regeneration process among vertebrate clades, where tooth regeneration refers to multiple tooth successors formed de novo for each tooth position in the jaws from a common set of retained dental progenitor cells. We discuss the conserved genetic mechanisms that might be modified to promote morphological diversity in replacement dentitions. We review current research and recent progress in this field during the last decade that have promoted our understanding of tooth diversity in an evolutionary developmental context, and show how tooth replacement and dental regeneration have impacted the evolution of the tooth-jaw module in vertebrates.

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Gene deployment for tooth replacement in the rainbow trout (Oncorhynchus mykiss): a developmental model for evolution of the osteichthyan dentition

Cited by 74 publications

References 39 publications

Evolved tooth gain in sticklebacks is associated with acis-regulatory allele ofBmp6

Evolved tooth gain in sticklebacks is associated with acis-regulatory allele ofBmp6

Replacing the first-generation dentition in pufferfish with a unique beak

Evolution and developmental diversity of tooth regeneration

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