Gender-specific Effect of Micronutrient on Non-erosive Reflux Disease and Erosive Esophagitis

Nam, Su Youn; Park, Bum-Joon; Cho, Yeong-Ah; Ryu, Kum Hei

doi:10.5056/jnm18114

Cited by 6 publications

(3 citation statements)

References 32 publications

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“…Symptomatic GERD, which is mainly diagnosed on the basis of the presence of heartburn or acid regurgitation, presents different clinical features and risk factors from RE 67. Several previous studies presented that difference in gender distribution exists in symptomatic GERD 3233. Although there is not a significantly big difference between both genders, women have a relatively high prevalence of symptomatic GERD.…”

Section: Discussionmentioning

confidence: 99%

Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease

et al. 2019

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Background Gender-related factors might play an important role in the development of reflux esophagitis (RE) and symptomatic gastro-esophageal reflux disease (GERD). We aimed to evaluate the prevalence and risk factors for RE and symptomatic GERD and determine whether gender specific differences exist. Methods This study was conducted on a health cohort consisting of 10,158 participants who underwent comprehensive health screening. Lifestyles and gastrointestinal symptoms were investigated using a self-reported structured questionnaire. Questionnaires about menstrual status were added for the women. Results The prevalence of RE in men was significantly higher than that in women (10.6% vs. 2.0%, P < 0.001); however, symptomatic GERD showed predominance in women (6.2% vs. 2.5%, P < 0.001). Although the prevalence of RE gradually increased with the duration of menopause stratified by decade ( P = 0.007), that of symptomatic GERD rapidly increased across the menopausal transit in women. Apart from common risk factors of obesity and current smoking for RE, over 70 years of age in women and hiatal hernia and hypertriglyceridemia in men were significant risk factors. In symptomatic GERD, high somatization was a common risk factor. Excessive alcohol drinking was a significant risk factor in men, but not in women. Conclusion This study showed a predominance of RE in men, but a predominance of symptomatic GERD in women. In women, dynamic increase in the prevalence of GERD is closely related to the menopause conditions and its duration. There are specific risk factors for RE and symptomatic GERD according to gender differences.

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Section: Discussionmentioning

confidence: 99%

Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease

et al. 2019

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“…In our study, increased iron intake associated with decreased risk of having ILD. We do note a previous study reports of an association between a decreased iron intake among patients with nonerosive esophageal reflux disease [30]. Reflux from gastric lesion is major etiology of laryngeal inflammation; therefore, reflux might mediate the association between iron intake and ILD.…”

Section: Plos Onementioning

confidence: 48%

Dietary factors associated with inflammatory laryngeal disease in South Korea

et al. 2020

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Laryngeal inflammation causes not only benign diseases of the larynx, such as laryngitis and granuloma, but also malignancy. Dietary factors are known to control or modulate the inflammatory reaction in the body. To date, the association between laryngeal inflammation and dietary factors has not been reported using nationwide population-based data. The aim of this study was to analyze the association between several dietary factors and inflammatory laryngeal disease in the Korean population. This study analyzed the data from Korean National Health and Nutrition Examination Surveys which is cross-sectional nationwide-population-based study. Association between the dietary nutrient intake and the prevalence of inflammatory laryngeal diseases was analyzed in 21,116 participants who underwent a laryngoscopy and filled in the dietary intake questionnaires. Of the 21,116 participants included in the analysis, 758 (3.59%) were diagnosed with inflammatory laryngeal disease. Prevalence of inflammatory laryngeal disease was higher in men (4.58%) than in women (2.84%). The mean age of patients was 53.77 years. When analyzing the risk using propensity score matching, ILD group tend to consume more coffee and to intake less fiber and iron than normal group. On Logistic regression analysis, an increased intake of carbohydrate, fiber, and iron was associated with lowered risk of having ILD in female. The association between inflammatory laryngeal disease and dietary factors was prominent in the group aged ≥50 years and female. Increased intake of fiber, iron, and vitamin A were associated with lower risk in the group aged ≥50 years. In female, increased intake of fiber, iron were associated with lower risk of having ILD. In the group aged ≤50 years, only an increased consumption of makgeolli, Korean traditional rice wine, was associated with a higher risk of ILD.

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“…It causes subjective problems to the patient and/or objectively provable changes on the esophagus mucous membrane (1). It is divided according to endoscopic finding into non-e ro sive (NERD) and erosive reflux disease (ERD) (2,3).…”

Section: Introductionmentioning

confidence: 99%

Surgical Therapy of Esophagus Reflux Disease

Smolár

Dedinská

Bobulova

et al. 2020

Acta Medica Martiniana

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Introduction: Fundoplication is the most frequently used action in the surgical treatment of gastroesophageal reflux disease (GERD). There are several types of fundoplication. The objective of our study was to identify complications after surgical treatment of GERD.Material and Methods: We determined several parameters of the monitored and we recorded complications related to surgery: occurrence of surgical, early and late post-surgical complications.Results: 52 patients (24 men and 28 women) with an average age of 53.3 years were included. The most frequently chosen type of fundoplication was Nissen-Rossetti. The most frequently occurring subjective post-surgery difficulties were temporal dysphagia (11.5%), sensation of nausea and vomiting after eating (3.8 %), pain in the surgical wound, and dyspnoea occurring in all patients after thoracotomy. Early post-surgery complication developed in 6 patients (11.5 %)Conclusion: Occurrence of complications in the group monitored by us was up to 11.5 % and perioperative mortality was 0 %. Hiatal hernia is frequently found in patients with GERD and it is considered to be one of the major causes for the development of this disease.

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Gender-specific Effect of Micronutrient on Non-erosive Reflux Disease and Erosive Esophagitis

Cited by 6 publications

References 32 publications

Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease

Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease

Dietary factors associated with inflammatory laryngeal disease in South Korea

Surgical Therapy of Esophagus Reflux Disease

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