Gender specific association of child abuse and adult cardiovascular disease in a sample of patients with Basal Cell Carcinoma

Hosang, Georgina M.; Johnson, Sheri L.; Kiecolt‐Glaser, Janice K.; Gregorio, Michael P. Di; Lambert, David; Bechtel, Mark; Hearne, Dean W.; Herron, Joel Bain; Glaser, Ronald

doi:10.1016/j.chiabu.2012.09.018

Cited by 27 publications

(18 citation statements)

References 35 publications

(60 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Less evidence exists for associations with psychosocial adversity in childhood. Previous studies have reported associations between specific types of psychosocial adversity in childhood and increased CVD risk;(Gooding et al, 2016; Hosang et al, 2013; Rich-Edwards et al, 2012; Thurston et al, 2014) particularly sexual and physical abuse. Very few studies have assessed associations of cumulative psychosocial adversity in childhood with multiple CVD risk factors in adulthood.…”

Section: Discussionmentioning

confidence: 99%

“…low head of household social class, household overcrowding and low parental education) is associated with cardiovascular disease (CVD) risk factors in adulthood (Galobardes, Smith, & Lynch, 2006; Havranek et al, 2015). However, there is much less evidence for associations of psychosocial adversity in childhood (for example, sexual abuse and physical neglect) with later CVD risk, and existing studies have reported both positive and null findings (Crowell et al, 2015; Gooding et al, 2016; Halonen et al, 2015; Hosang et al, 2013; Rich-Edwards et al, 2012; Su et al, 2015; Thurston et al, 2014). The Adverse Childhood Experiences (ACE) study has been pivotal in characterising medium and long-term health outcomes of psychosocial adversity in childhood and Felitti et al have previously reported a strong graded relationship between the number of categories of retrospectively reported adverse childhood exposures and the presence of CVD (including ischemic heart disease) in a study of 9508 adults (Felitti et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

“…Existing studies have reported associations between specific types of psychosocial adversity, particularly sexual or physical abuse, (Gooding et al, 2016; Hosang et al, 2013; Rich-Edwards et al, 2012; Thurston et al, 2014) with increased CVD risk. However, few studies have considered a possible cumulative effect of exposure to multiple types of adversity in childhood (Crowell et al, 2015; Halonen et al, 2015; Su et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood

Anderson

Fraser

Caleyachetty

et al. 2018

Child Abuse & Neglect

View full text Add to dashboard Cite

Studies assessing associations of childhood psychosocial adversity (e.g. sexual abuse, physical neglect, parental death), as opposed to socioeconomic adversity, with cardiovascular disease (CVD) risk factors in adulthood are scarce. The aim of this study is to assess associations of various types of psychosocial adversity and cumulative adversity in childhood, with multiple CVD risk factors in mid-life. At study enrolment, women from the Avon Longitudinal Study of Parents and Children (N = 3612) retrospectively reported: lack of maternal care, maternal overprotection, parental mental illness, household dysfunction, sexual abuse, physical and emotional abuse, and neglect in childhood. Approximately 23 years later, body mass index (BMI), waist circumference, systolic and diastolic blood pressure, plasma glucose, insulin, triglycerides, low and high density lipoprotein cholesterol, C-reactive protein, carotid intima-media thickness (cIMT) and arterial distensibility were assessed (mean age 51 years). We examined associations of each specific type of psychosocial adversity and cumulative adversity with CVD risk factors. No specific type of psychosocial adversity was consistently associated with the CVD risk factors. There was evidence that a one standard deviation greater cumulative psychosocial adversity was associated with 0.51 cm greater waist circumference (95% confidence interval [CI]: 0.02 cm, 1.00 cm, p = 0.04) and a lower arterial distensibility, even after adjustment for age, ethnicity and childhood and adult socioeconomic position. We found no consistent evidence that any specific type of psychosocial adversity, or cumulative psychosocial adversity in childhood, is associated with CVD risk factors in adult women.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood

Anderson

Fraser

Caleyachetty

et al. 2018

Child Abuse & Neglect

View full text Add to dashboard Cite

show abstract

“…We did not have data on other potentially confounding factors such as childhood adversity. For example, individuals who have experienced childhood abuse, especially women, are more likely to have less adaptive intimate interactions and be at risk for cardiovascular disease (42–44). …”

Section: Discussionmentioning

confidence: 99%

Daily Marital Interaction Quality and Carotid Artery Intima-Medial Thickness in Healthy Middle-Aged Adults

Joseph

Kamarck

Muldoon

et al. 2014

Psychosomatic Medicine

View full text Add to dashboard Cite

Objective To examine the association between marital interaction quality during daily life and subclinical cardiovascular disease (CVD). Studies have shown that marital status and quality of marriage are associated with cardiovascular health. However, little is known about the role of marital interaction quality during daily life in contributing to these effects. Methods The sample consisted of 281 healthy, employed middle-aged adults who were married or living with a partner in a marital-like relationship (mean age = 42.0 years, 88% white, 52% men). Marital interaction quality was assessed using hourly real-time Ecological Momentary Assessments (EMAs) for 4 days, with participants rating their current or recent partner interactions on positive and negative characteristics (e.g., agreeableness and conflict). Carotid artery intima medial thickness (IMT) was assessed using ultrasound imaging. Results Adjusting for demographics, positive marital interaction was inversely associated with IMT, [b = −.02 F(1, 275) = 9.18, p = .002], and negative marital interaction was positively associated with IMT, [b = .02 F(1, 275) = 10.29, p = .001]. These associations were not accounted for by behavioral and biological cardiovascular disease (CVD) risk factors and were consistent across age, sex, race, and education. The associations were also independent of marital interaction frequency, nonmarital social interaction quality, and personality factors. Global reports of marital quality, in contrast, were not associated with IMT. Conclusions Marital quality as measured during real-time interactions between partners was associated with subclinical cardiovascular disease in healthy middle-aged adults. This study supports the utility of real-time social interaction assessment for characterizing links between social relationships and cardiovascular health.

show abstract

“…Childhood adversity is a non-specific risk factor and has been linked to other emotional problems [18], psychiatric illnesses [16,19,20] and physical disorders [21,22]. A better understanding of the specific mechanisms that underlie the childhood adversity/depression association is needed.…”

Section: Childhood Adversitymentioning

confidence: 99%

Interaction between stress and the BDNF Val66Met polymorphism in depression: A systematic review and meta-analysis

Hosang¹,

Shiles²,

McGuffin³

et al. 2014

Comprehensive Psychiatry

Self Cite

View full text Add to dashboard Cite

Background: Major depression is a disabling psychiatric illness with complex origins. Life stress (childhood adversity and recent stressful events) is a robust risk factor for depression. The relationship between life stress and Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene has received much attention. The aim of the present work was to review and conduct a meta-analysis on the results from published studies examining this interaction. Methods: A literature search was conducted using PsychINFO and PubMed databases until 22 November 2013. A total of 22 studies with a pooled total of 14,233 participants met the inclusion criteria, the results of which were combined and a meta-analysis performed using the Liptak-Stouffer z-score method. Results: The results suggest that the Met allele of BDNF Val66Met significantly moderates the relationship between life stress and depression (P = 0.03). When the studies were stratified by type of environmental stressor, the evidence was stronger for an interaction with stressful life events (P = 0.01) and weaker for interaction of BDNF Val66Met with childhood adversity (P = 0.051). Conclusions:The interaction between BDNF and life stress in depression is stronger for stressful life events rather than childhood adversity. Methodological limitations of existing studies include poor measurement of life stress.

show abstract

Gender specific association of child abuse and adult cardiovascular disease in a sample of patients with Basal Cell Carcinoma

Cited by 27 publications

References 35 publications

Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood

Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood

Daily Marital Interaction Quality and Carotid Artery Intima-Medial Thickness in Healthy Middle-Aged Adults

Interaction between stress and the BDNF Val66Met polymorphism in depression: A systematic review and meta-analysis

Contact Info

Product

Resources

About