Gender-related Differences in Risk factors and Treatment Strategies in Patients with Acute Coronary Syndrome across Egypt: part of the Cardio- Risk Project

Reda, Ashraf; Ashraf, Mohamed; Soliman, Mahmoud A.; Ragy, Hany; Elkersh, Ahmed; Abdou, Waleed; Mostafa, Tamer; Hassan, Muhammed A.; Farag, Elsayed; Khamis, Hazem; Magdy, Moheb; Elbahry, Atef; Salama, Sameh; Kazamel, Ghada; Sadaka, M; Mostafa, Morsy; El-Bary, Akram Abd; Sanad, Osama; Rafla, Samir; El-Hady, Yaser Abd; Selim, Mohammed; Farag, Nabil; Elghawaby, Helmy; Elaraby, Hosam H; Emil, Sameh; Beshay, Morad; Shawky, Ahmed M.; Yusef, Mahmoud; El-Ghany, Mohammed Abd; Gamal, Awni; Baghdady, Yaser; Mostafa, Taymour; Zahran, Mohammed; Rabat, Khaled; Elshorbagy, Amany K.

doi:10.1016/j.atherosclerosissup.2018.07.045

Cited by 4 publications

(6 citation statements)

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“…The EMR includes countries of the Arabian Gulf, Middle East and Northern Africa (MENA), and Western Asia. Large ACS registries and sex-specific analyses exist in the region, particularly from Saudi Arabia [ 18 , 20 ], the United Arab Emirates (UAE) [ 17 , 96 , 97 ], Egypt [ 98 ] and Pakistan [ 99 ].…”

Section: Eastern Mediterranean Region (Emr)mentioning

confidence: 99%

“…Recently, a shift from the recognized tendency to treat men more aggressively has been demonstrated. The Egyptian CardioRisk study found no gender differences in most diagnostic and therapeutic procedures, including primary PCI [ 98 ]. In the Saudi Acute Myocardial Infarction Registry Program (STARS-1 Program), implementation of GDMT did not differ based on sex, despite women being older with more CV risk factors [ 18 ].…”

Section: Eastern Mediterranean Region (Emr)mentioning

confidence: 99%

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Sex Differences in Acute Coronary Syndromes: A Global Perspective

Cader

Banerjee

Gulati

2022

JCDD

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Despite increasing evidence and improvements in the care of acute coronary syndromes (ACS), sex disparities in presentation, comorbidities, access to care and invasive therapies remain, even in the most developed countries. Much of the currently available data are derived from more developed regions of the world, particularly Europe and the Americas. In contrast, in more resource-constrained settings, especially in Sub-Saharan Africa and some parts of Asia, more data are needed to identify the prevalence of sex disparities in ACS, as well as factors responsible for these disparities, particularly cultural, socioeconomic, educational and psychosocial. This review summarizes the available evidence of sex differences in ACS, including risk factors, pathophysiology and biases in care from a global perspective, with a focus on each of the six different World Health Organization (WHO) regions of the world. Regional trends and disparities, gaps in evidence and solutions to mitigate these disparities are also discussed.

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Section: Eastern Mediterranean Region (Emr)mentioning

confidence: 99%

Section: Eastern Mediterranean Region (Emr)mentioning

confidence: 99%

Sex Differences in Acute Coronary Syndromes: A Global Perspective

Cader

Banerjee

Gulati

2022

JCDD

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“…Other studies from Egypt did not show sex differences in terms of utilization of diagnostic and therapeutic procedures or adverse outcomes (Table 1). 50,51 In Tunisia between 1997 and 2003, the ACS mortality rates increased more rapidly in women compared with men (23.8% versus 11.8%), attributed to unfavorable lifestyle changes and westernization. 52 Additionally, women from Tunisia presented later after onset of symptoms compared with men (median of 3 versus 2 hours).…”

Section: Geographic and Socioeconomic Disparitiesmentioning

confidence: 99%

Sex, Racial, and Ethnic Disparities in Acute Coronary Syndrome: Novel Risk Factors and Recommendations for Earlier Diagnosis to Improve Outcomes

Khraishah

Daher

Garelnabi

et al. 2023

ATVB

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In this review, sex, racial, and ethnic differences in acute coronary syndromes on a global scale are summarized. The relationship between disparities in presentation and management of acute coronary syndromes and effect on worse clinical outcomes in acute coronary syndromes are discussed. The effect of demographic, geographic, racial, and ethnic factors on acute coronary syndrome care disparities are reviewed. Differences in risk factors including systemic inflammatory disorders and pregnancy-related factors and the pathophysiology underlying them are discussed. Finally, breast arterial calcification and coronary calcium scoring are discussed as methods to detect subclinical atherosclerosis and start early treatment in an attempt to prevent clinical disease.

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“…The INTERHEART study showed that there were potentially modifiable risk factors for ACS including raised Apo B/Apo A ratio, current smoking status, psychosocial factors, diabetes, hypertension, abdominal obesity, alcohol consumption, regular physical activity and daily consumption of fruits and vegetables [ 20 ]. Further, a gender specific pattern of risk factors has become apparent globally, with women presenting with ACS having high rate of hypertension, diabetes mellitus and obesity as opposed to men [ 21 , 22 ]. Moreover, globally there is a tendency for female patients to receive less aggressive invasive and pharmacological treatment after ACS [ 21 , 22 ].…”

Section: Introductionmentioning

confidence: 99%

“…Further, a gender specific pattern of risk factors has become apparent globally, with women presenting with ACS having high rate of hypertension, diabetes mellitus and obesity as opposed to men [ 21 , 22 ]. Moreover, globally there is a tendency for female patients to receive less aggressive invasive and pharmacological treatment after ACS [ 21 , 22 ].…”

Section: Introductionmentioning

confidence: 99%

Epidemiology and the Magnitude of Coronary Artery Disease and Acute Coronary Syndrome: A Narrative Review

Ralapanawa¹,

Sivakanesan²

2021

JEGH

314

147

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Coronary Artery Disease (CAD) is characterized by the presence of atherosclerosis in coronary arteries and it can be asymptomatic. Coronary Heart Disease (CHD)/Ischaemic Heart Disease (IHD) includes the diagnosis of Stable angina, Acute Coronary Syndrome (ACS) and silent myocardial ischaemia and mortality from CHD results from CAD. ACS almost always presents with a symptom and includes unstable angina and myocardial infarction. For simplicity, herein we will refer to CHD as CAD.

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Gender-related Differences in Risk factors and Treatment Strategies in Patients with Acute Coronary Syndrome across Egypt: part of the Cardio- Risk Project

Cited by 4 publications

References 0 publications

Sex Differences in Acute Coronary Syndromes: A Global Perspective

Sex Differences in Acute Coronary Syndromes: A Global Perspective

Sex, Racial, and Ethnic Disparities in Acute Coronary Syndrome: Novel Risk Factors and Recommendations for Earlier Diagnosis to Improve Outcomes

Epidemiology and the Magnitude of Coronary Artery Disease and Acute Coronary Syndrome: A Narrative Review

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