Gender-related differences in outcomes and resource utilization in patients undergoing radiofrequency ablation of supraventricular tachycardia: results from Patients' Perspective on Radiofrequency Catheter Ablation of AVRT and AVNRT Study

“…One probable explanation of this finding is the higher proportion of additional tests to exclude concomitant diseases especially coronary artery disease (CAD) in older patients since chest discomfort and dyspnea accompanying arrhythmia may mimic CAD. In our previous analysis, men were more likely to undergo echocardiography and stress testing mainly to exclude significant CAD [9]. This is important since older patients with AVNRT are not uncommon [14].…”

Section: Discussionmentioning

confidence: 99%

“…This was a pre-specified subanalysis of the Patients’ Perspective on Radiofrequency Catheter Ablation of AVRT and AVNRT (PPRA) Study (NCT01594814) [9]. PPRA was a single-center, prospective, cohort study performed in a tertiary-care cardiological center.…”

Section: Methodsmentioning

confidence: 99%

“…The summary index equal to “1” means no problems at all while −0.55 means extreme problems in all five dimensions and the worst measurable health state. In our previous analysis, the EQ-5D-3L accurately described the quality of life of patients with different numbers and lengths of arrhythmia episodes and different accompanying signs and symptoms and arrhythmia’s influence on everyday life [9]. To take into account all those factors and simplify the present analysis, we decided to use the summary index of EQ-5D-3L as a single measure of the “severity” of the arrhythmia.…”

Section: Methodsmentioning

confidence: 99%

“…While atrial fibrillation remains the main target of RFA in many countries, SVTs remain a significant portion of RFA procedures in Europe [8]. The relatively non-specific clinical presentation and frequent problems to obtain the electrocardiographical (ECG) documentation of those arrhythmias lead to a long gap between the onset of symptoms and RFA which in many cases may exceed 15 years [5, 9, 10]. Costs of medical treatment of SVT: repetitive consultations, hospitalizations, and diagnostic tests, due to recurrent episodes of arrhythmias before the RFA may be substantial [1].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Patient’s age rather than severity of the arrhythmia influences the cost of medical treatment of atrioventricular nodal or atrioventricular reciprocating tachycardia

Farkowski

Pytkowski²,

Maciąg³

et al. 2016

J Interv Card Electrophysiol

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PurposeRadiofrequency ablation (RFA) is considered the treatment of choice in cases of atrioventricular nodal reciprocating tachycardia (AVNRT) and atrioventricular reciprocating tachycardia (AVRT). Published studies suggest a considerable time gap between the onset of the arrhythmia, correct diagnosis, and RFA which may reach 10–15 years. The cost of medical treatment during that period may be substantial. The aim of the study was to calculate the annual direct medical cost of medical treatment of patients with AVNRT and AVRT and identify potential factors influencing this cost.MethodsBased on the consumption of particular resources and the unit costs of services in 2013, we calculated the annual direct medical cost of care for patients with AVNRT and AVRT in Poland. We adopted the public payer’s and societal perspectives. Data on health resources was collected with a structured questionnaire and medical records of patients scheduled for RFA. Additional analyses were performed to identify factors influencing this cost.ResultsWe enrolled 82 patients: mean age 43.9 ± 14.1 years old and mean symptom duration before the RFA 13.0 ± 11.3 years. The median annual cost of medical treatment was 546 USD [312–957], 411 € [278–786], and 616 USD [369–1044], 464 € [235–721], for the public payer and the common perspective, respectively, with hospitalizations being the main cost component. In multivariate analysis, only the age of the patient significantly influenced this cost.ConclusionsThe annual cost of medical treatment of AVNRT or AVRT is substantial and dependent on the age of the patient rather than the severity of the arrhythmia (NCT01594814).

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Evaluation of the effects of isoproterenol on arrhythmia recurrence following catheter ablation in patients with atrioventricular nodal re‐entrant tachycardia: A randomized controlled clinical trial

Lotfabadi

Mehrabi

Heidari‐Bakavoli

et al. 2023

Pharmacology Res & Perspec

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We aimed to determine the effects of isoproterenol on arrhythmia recurrence in atrioventricular nodal re‐entrant tachycardia (AVNRT) patients treated with catheter ablation. The present randomized controlled clinical trial was conducted on AVNRT patients candidates for radiofrequency ablation (RFA). The patients were randomly assigned to receive isoproterenol (0.5–4 μg/min) or not (control group) for arrhythmia re‐induction after ablation. The results of the electrophysiological (EP) study, the ablation parameters, and the arrhythmia recurrence rate were recorded. We evaluated 206 patients (53 males and 153 females) with a mean (SD) age of 49.87 (15.5) years in two groups of isoproterenol ( n = 103) and control ( n = 103). No statistically significant difference was observed between the two studied groups in age, gender, EP study, and ablation parameters. The success rate of ablation was 100% in both groups. During ~16.5 months of follow‐up, one patient (1%) in the isoproterenol group and four patients (3.8%) in the control group experienced AVNRT recurrence (HR = 0.245; 95% confidence interval [CI], 0.043–1.418; p = .173). Based on the Kaplan–Meier analysis, there was no significant difference in the incidence rate of arrhythmia recurrence during the follow‐up period between the two studied groups ( p = .129). Additionally, there were no significant differences between the arrhythmia's recurrence according to age, gender, junctional rhythm, type of AVNRT arrhythmia, and DAVN persistence after ablation. Although isoproterenol administration for arrhythmia re‐induction after ablation did not alleviate the treatment outcomes and arrhythmia recurrence following RFA in AVNRT patients, further studies with a larger sample size and a longer duration of follow‐up are necessary.

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Gender-related differences in outcomes and resource utilization in patients undergoing radiofrequency ablation of supraventricular tachycardia: results from Patients' Perspective on Radiofrequency Catheter Ablation of AVRT and AVNRT Study

Abstract: There is a small but significant gender-related difference in outcome of RFA in patients with AVNRT or AVRT measured with a disease-specific instrument. No significant difference in HRQoL or access to healthcare resources between women and men was found.

Cited by 44 publications

References 26 publications

Symptom challenges after atrial fibrillation ablation

Symptom challenges after atrial fibrillation ablation

Patient’s age rather than severity of the arrhythmia influences the cost of medical treatment of atrioventricular nodal or atrioventricular reciprocating tachycardia

Evaluation of the effects of isoproterenol on arrhythmia recurrence following catheter ablation in patients with atrioventricular nodal re‐entrant tachycardia: A randomized controlled clinical trial

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