Gender medicine: Towards a gender-specific treatment of neuropsychiatric disorders

Biskup, Ewelina; Martínková, J; Ferretti, Maria Teresa

doi:10.1016/b978-0-444-64123-6.00029-1

Cited by 9 publications

(8 citation statements)

References 118 publications

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“…There is substantial evidence that gender disparities exist in neurologic and neuropsychiatric disorders among the pediatric population as already reported in adults [ 7 ]. Our literature analysis supports the fact that new guidelines should take this into account because there are still important gaps in the sector that need to be filled.…”

Section: Discussionmentioning

confidence: 99%

“…Even if the examples of such applications in pediatrics are fewer, it has been shown in other medicinal areas how gender can actually affect the human pathology. As reported by Biskup et al, several studies conducted among adult patients have reported a strong association between gender and neuropsychiatric disorders (such as Alzheimer disease, schizophrenia and depression) [ 7 ]. The purpose of this review is to frame the most recent knowledge about the role of gender assigned at birth on the neurological development and neuropsychiatric disorders among young people.…”

Section: Introductionmentioning

confidence: 99%

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A Gender-Based Point of View in Pediatric Neurology

Diana

Esposito

2023

JPM

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While the significance of gender has only recently been recognized, gender assigned at birth has long been understood to have a significant influence on a number of illnesses. Due to the paucity of data in this regard in pediatrics, the purpose of this narrative review is to frame the most recent knowledge about the role of gender assigned at birth in the neurological development and neuropsychiatric disorders among young people. Literature analysis showed that gender disparities exist in neurologic and neuropsychiatric disorders among the pediatric population and supported the fact that new guidelines should take this into account. However, there is an urgent need for specific studies focused on gender role among children and adolescents in order to better understand how this can relate to diagnosis, development and treatment of different neurologic and neuropsychiatric diseases. Moreover, further efforts should be directed to identify unique risks linked to gender disorders and gender dysphoria as well as taking into account a gender point of view when approaching a pediatric patient.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Gender-Based Point of View in Pediatric Neurology

Diana

Esposito

2023

JPM

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“…Genel olarak tanımlar incelendiğinde, biyolojik cinsiyet bir canlının doğuştan getirdiği, genetik yolla belirlenen ve cinsel üreme organına göre farklılık gösteren bir biyolojik özelliktir. Toplumsal cinsiyet ise insanların, toplumların ve kültürlerin kadın ve erkeklere yüklemiş olduğu rolleri ve sorumlulukları içerir (Biskup, Martinkova ve Ferretti, 2020). Bu nedenle toplumsal cinsiyet kavramı öğrenilebilen bir yapı olarak kabul edilebilir (Henderson, 2015).…”

Section: Literatür Taramasıunclassified

Medyada Toplumsal Cinsiyet Eşitsizliği: Bebek Bezi Reklamlarının İncelenmesi

Alabay

2023

Anadolu Üniversitesi Sosyal Bilimler Dergisi

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Bu araştırmada Türkiye’de satışı olan ve televizyonda reklamları bulunan bebek bezi firmalarının reklamlarının hem görsel hem de dilsel öğelerinin toplumsal cinsiyet açısından incelenmesi amaçlanmıştır. Araştırma nitel araştırma modeli ile gerçekleştirilmiştir. Araştırmanın çalışma grubunu 9 farklı markanın toplam 37 adet bebek bezi reklamı oluşturmaktadır. Çalışmanın verilerinin kaydedilmesinde araştırmacı tarafından geliştirilen ve uzman görüşleri alınmış olan “Bebek Bezi Reklamları Doküman Analiz Formu” kullanılmıştır. Araştırma sonucunda bebek bezi reklamlarının büyük bir oranının kadınlar tarafından seslendirildiği ve reklamların yarısından fazlasında toplumsal cinsiyet eşitsizliğine yol açan mesajlara yer verildiği sonucuna ulaşılmıştır. Reklamlarda oynatılan oyuncuların da çoğunlukla kadın oyuncular olduğu tespit edilmiştir. Ayrıca reklamlarda oynayan kadın oyunculara alışveriş yapan ve misafir ağırlayan kişi rollerinin verildiği gözlemlenmiştir. Sonuç olarak Türkiye’de televizyonlardaki bebek bezi reklamlarının çoğunun toplumsal cinsiyet eşitsizliğini besleyen bir yapıda olduğu söylenebilir.

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“…However, it should be noted that these findings are likely confounded by biological factors of sex. Research has also found that sex and gender are major influencing factors in NPD presentation and outcome ( 74 ). This has led to a call for inclusion of gender and sex in a more tailored approach to NPD diagnosis and treatment ( 74 ).…”

Section: Anthropological Insights Into Microbiome Research With Impli...mentioning

confidence: 99%

“…Research has also found that sex and gender are major influencing factors in NPD presentation and outcome ( 74 ). This has led to a call for inclusion of gender and sex in a more tailored approach to NPD diagnosis and treatment ( 74 ). Therefore, it is important that such research be expanded to include the wider spectrum of gender identities in order to assess how the social constructs of gender may play a role in shaping the relationship between oral microbiota and NPDs.…”

Section: Anthropological Insights Into Microbiome Research With Impli...mentioning

confidence: 99%

The Oral-Microbiome-Brain Axis and Neuropsychiatric Disorders: An Anthropological Perspective

Bowland

Weyrich

2022

Front. Psychiatry

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In the 21st century, neuropsychiatric disorders (NPDs) are on the rise, yet the causal mechanisms behind this global epidemic remain poorly understood. A key to these unknowns may lie within the vast communities of bacteria, fungi, and viruses in the body (microbiota), which are intimately linked with health and disease. NPDs were recently shown to be connected to gut microbiota, which can communicate with and influence the brain through the Gut-Brain-Axis (GBA). Parallel studies examining oral microbiota and their connections to the brain also suggest that microbes in the mouth can similarly influence NPD outcomes. However, the mechanisms and pathways that illuminate how oral microbiota and brain communicate in NPDs remain unknown. Here, we review identified mechanisms and pathways that oral microbiota use to engage the brain, and we lay the theoretical foundation for an oral-microbiota-brain axis (OMBA). Specifically, we examine established neuroinflammatory and immune system activation responses that underpin interactions between the oral microbiota and the central nervous system (CNS), detailing four specific mechanisms: (1) microbial and metabolite escape, (2) neuroinflammation, (3) CNS signaling, and (4) response to neurohormones. We then scrutinize why including the OMBA, in addition to the GBA, is critically needed to elucidate specific causal relationships between microbial dysbiosis and observed NPD development and progression. Furthermore, we argue for comprehensive, interdisciplinary approaches that integrate lab-based microbiome research and population-level studies that examine the OMBA to improve NPDs. We specifically identify key anthropological perspectives that integrate sociocultural, epidemiological, genetic, and environmental factors that shape the oral microbiome and its interactions with NPDs. Together, future studies of the OMBA in conjunction with interdisciplinary approaches can be used to identify NPD risks and improve outcomes, as well as develop novel intervention and treatment strategies.

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Gender medicine: Towards a gender-specific treatment of neuropsychiatric disorders

Cited by 9 publications

References 118 publications

A Gender-Based Point of View in Pediatric Neurology

A Gender-Based Point of View in Pediatric Neurology

Medyada Toplumsal Cinsiyet Eşitsizliği: Bebek Bezi Reklamlarının İncelenmesi

The Oral-Microbiome-Brain Axis and Neuropsychiatric Disorders: An Anthropological Perspective

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