Gender issues in epilepsy—The science of why it is special

Taubøll, Erik; Luef, Gerhard

doi:10.1016/j.seizure.2007.11.006

Cited by 14 publications

(4 citation statements)

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“…Epilepsy is one of the most common, serious, chronic neurological conditions in the world and it is becoming increasingly evident that a number of factors affect quality of life and well being in men and women with epilepsy beyond simple seizure control (1). However, historically, gender differences in epilepsy focused mainly on women with epilepsy, and issues around menstrual cycles, contraception and pregnancy.…”

Section: Introductionmentioning

confidence: 99%

“…However, historically, gender differences in epilepsy focused mainly on women with epilepsy, and issues around menstrual cycles, contraception and pregnancy. More recently there has been increasing awareness of the differing impact of epilepsy and antiepileptic drug (AED) treatment on sexual function in both men and women (1) and that sexual well-being is critical for a good quality of life in patients with epilepsy (2).…”

Section: Introductionmentioning

confidence: 99%

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Sexual Dysfunction in Epilepsy and the Role of Anti-Epileptic Drugs

Yogarajah

Mula

2018

CPD

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Sexual Dysfunction in Epilepsy and the Role of Anti-Epileptic Drugs

Yogarajah

Mula

2018

CPD

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“…[1] Seizures do not occur accidentally and occur in clusters or consecutively in men and women developing the epilepsy. It can also occur periodically.…”

Section: Introductionmentioning

confidence: 99%

“…[234] Epileptic females differ from epileptic males, as the patients with epilepsy are faced with social and physical problems associated with sex and it seems that the issue of sex in epilepsy is focused on in recent decades. [1]…”

Section: Introductionmentioning

confidence: 99%

Progesterone therapy in women with intractable catamenial epilepsy

Najafi¹,

Sadeghi²,

Mehvari³

et al. 2013

Adv Biomed Res

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Background:Catamenial epilepsy is a kind of epilepsy, known in this name, when the periodicity of the exacerbation of the seizure is in association with menstural cycle. The present study examined the progesterone effectiveness as a complementary treatment in women with intractable catamenial epilepsy.Materials and Methods:The present study was conducted as a double-blind randomized controlled trial on 38 women with intractable catamenial epilepsy. Patients were assessed in two groups: The case group received in addition to AEDs, two (Mejestrol) 40 mg progesterone tablets in the second half of the cycle from 15th to 25th day. And the control group received in addition to AEDs, two placebo tablets daily. Age, BMI, epilepsy duration, types of the drugs used, progesterone level, and the number of the seizures in 3 months before and after the study were compared.Results:Based on the results of which there was no statistically significant difference in regard to age, BMI, epilepsy duration, types of the drugs used, progesterone level between the case and the control groups (P-value > 0.05). The number of the seizures after treatment has significantly decreased compared to before-treatment state. The degree of decreasing in the case group receiving the progesterone was higher than in the control group receiving the placebo. The difference, thus, is significant, based on statistical tests (P-value = 0.024).Conclusion:Based on the findings of this study using progesterone in women with intractable catamenial epilepsy has a significant effect on the degree of decreasing in the number of the seizures.

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Impact of Epilepsy and AEDs on Reproductive Health

Luef¹

2013

Epilepsy in Women

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Gender issues in epilepsy—The science of why it is special

Cited by 14 publications

References 0 publications

Sexual Dysfunction in Epilepsy and the Role of Anti-Epileptic Drugs

Sexual Dysfunction in Epilepsy and the Role of Anti-Epileptic Drugs

Progesterone therapy in women with intractable catamenial epilepsy

Impact of Epilepsy and AEDs on Reproductive Health

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