Gender is a Significant Factor for Failure of Metal-on-Metal Total Hip Arthroplasty

Latteier, Michael J.; Berend, Keith R.; Lombardi, Adolph V.; Ajluni, Andrew F.; Seng, Brian E.; Adams, Joanne B.

doi:10.1016/j.arth.2011.04.012

Cited by 46 publications

(29 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The current study indirectly supports previous reports that females have greater immune reactivity to orthopaedic metal debris [9] and experience a greater incidence of autoimmune disease [3] than males. However, it is unclear how much of the current study's findings are due to inherent gender difference and not pseudotumor metal-related immune response.…”

Section: Where Do We Need To Go?supporting

confidence: 80%

CORR Insights®: Do Patients With a Failed Metal-on-metal Hip Implant With a Pseudotumor Present Differences in Their Peripheral Blood Lymphocyte Subpopulations?

Hallab

2015

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

show abstract

Section: Where Do We Need To Go?supporting

confidence: 80%

CORR Insights®: Do Patients With a Failed Metal-on-metal Hip Implant With a Pseudotumor Present Differences in Their Peripheral Blood Lymphocyte Subpopulations?

Hallab

2015

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

show abstract

“…31 Increased acetabular anteversion in women occurs as a consequence of increased lumbar lordosis 32 and may also contribute to edge loading. This increased dynamic and postural anteversion cannot be detected with conventional radiographs.There may also be gender-specific differences in the head-neck offset 33 and angulation of the femoral neck 34 that contribute to the poorer survival in women. Furthermore, the constant stem thickness across all sizes of the BHR predisposes the narrower femoral neck of women to greater compromise.…”

Section: Discussionmentioning

confidence: 99%

Birmingham hip resurfacing at a mean of ten years

Coulter¹,

Young²,

Dalziel³

et al. 2012

The Journal of Bone and Joint Surgery. British volume

117

106

View full text Add to dashboard Cite

We report the findings of an independent review of 230 consecutive Birmingham hip resurfacings (BHRs) in 213 patients (230 hips) at a mean follow-up of 10.4 years (9.6 to 11.7). A total of 11 hips underwent revision; six patients (six hips) died from unrelated causes; and 13 patients (16 hips) were lost to follow-up. The survival rate for the whole cohort was 94.5% (95% confidence interval (CI) 90.1 to 96.9). The survival rate in women was 89.1% (95% CI 79.2 to 94.4) and in men was 97.5% (95% CI 92.4 to 99.2). Women were 1.4 times more likely to suffer failure than men. For each millimetre increase in component size there was a 19% lower chance of a failure. The mean Oxford hip score was 45.0 (median 47.0, 28 to 48); mean University of California, Los Angeles activity score was 7.4 (median 8.0, 3 to 9); mean patient satisfaction score was 1.4 (median 1.0, 0 to 9). A total of eight hips had lysis in the femoral neck and two hips had acetabular lysis. One hip had progressive radiological changes around the peg of the femoral component. There was no evidence of progressive neck narrowing between five and ten years. Our results confirm that BHR provides good functional outcome and durability for men, at a mean follow-up of ten years. We are now reluctant to undertake hip resurfacing in women with this implant.

show abstract

“…steep inclination and high version angles [9], low coverage of the head with cup [10], edge loading [11], female sex [12], etc. the mechanism of failure is not well understood.…”

Section: Introductionmentioning

confidence: 99%

The effect of contact load on CoCrMo wear and the formation and retention of tribofilms

Wimmer

Michel

Mathew

et al. 2015

Wear

View full text Add to dashboard Cite

Tribochemical reactions in a protein lubricated metal-on-metal (MoM) sliding contact may play a significant role for its wear performance. Such reactions lead to the formation of a carbonaceous ‘tribofilm’, which can act as a protective layer against corrosion and wear. The purpose of this study was to determine the effect of contact load on wear and the formation and retention of tribofilms. Wear tests were performed in a custom-made ball-on-flat testing apparatus that incorporated an electrochemical cell. A ceramic ball was used to articulate against low-carbon wrought CoCrMo alloy pins in bovine serum. Using a range of contact loads at a single potentiostatic condition (close to free potential), weight loss and changes in surface properties were evaluated. We determined that wear was influenced by the loading condition. As expected, wear increased with load, but the association between applied load and measured weight loss was not linear. In the intermediate load region, in the range of 32–48 N (~58–80 MPa), there was more than an order of magnitude drop in the wear per unit load, and the wear versus load data suggested an inflexion point at 49 N. Regression analyses yielded a cubic model (R2=0.991; p=0.0002), where the cubic term, which represents the inflexion, was highly significant (p=0.0021). This model is supported by the observations that the minimum in the friction versus load curve is at 52 N and the highest relative increase in polarization resistance occurred at 49 N. Scanning electron microscopy and Raman spectroscopy indicated the absence of a tribofilm for the low and within the contact area of the high load cases. Synergistic interactions of wear and corrosion seem to play an important role.

show abstract

Gender is a Significant Factor for Failure of Metal-on-Metal Total Hip Arthroplasty

Cited by 46 publications

References 15 publications

CORR Insights®: Do Patients With a Failed Metal-on-metal Hip Implant With a Pseudotumor Present Differences in Their Peripheral Blood Lymphocyte Subpopulations?

CORR Insights®: Do Patients With a Failed Metal-on-metal Hip Implant With a Pseudotumor Present Differences in Their Peripheral Blood Lymphocyte Subpopulations?

Birmingham hip resurfacing at a mean of ten years

The effect of contact load on CoCrMo wear and the formation and retention of tribofilms

Contact Info

Product

Resources

About