Gender effects on esophageal motility

Dantas, Roberto Oliveira; Ferriolli, Eduardo; Souza, Marilene Alícia

doi:10.1590/s0100-879x1998000400011

Cited by 33 publications

(37 citation statements)

References 13 publications

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“…A hipótese é que homens e mulheres têm diferenças na motilidade do esôfago. Métodos -Manometria de alta resolução foi realizada em voluntários saudáveis, 10 homens [média de idade: 37,7 (8,1) anos] e 12 mulheres [média de idade: 38,7 (7,5) anos], na posição sentada e com 10 deglutições de 5 mL de solução salina. Foram avaliadas a pressão integrada de relaxamento do esfíncter inferior do esôfago, velocidade da contração peristáltica, integral da contração distal, latência distal, extensão da contração proximal, duração da contração proximal >30 mmHg, duração da contração proximal, integral da contração proximal, pressão máxima do esfíncter superior do esôfago.…”

Section: Author' Contributionsunclassified

“…The investigations about gender influence on esophageal motility have described that: integrated relaxation pressure of the lower esophageal sphincter (LES) is higher in women than in men (11) ; contractions in proximal esophagus have a higher area under the curve in women (7) ; women have an increase in contraction duration in distal esophagus (8) ; women have a higher LES pressure, higher distal amplitude, longer distal contraction duration and slower distal velocity of peristaltic contraction (14) . Gender does not influence whether esophageal motility is normal, spastic or with a non-specific motor disorder (1) .…”

Section: Introductionmentioning

confidence: 99%

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Esophageal Motility in Men and Women Evaluated by High-Resolution Manometry

Costa

Dantas

2017

Arq. Gastroenterol.

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-Background -Esophageal motility has been described in the literature as having differences between men and women. Most of these investigations use the water perfusion method for esophageal manometry. In this investigation the esophageal motility of men and women was compared with high-resolution manometry of the esophagus. Objective -To compare the esophageal motility of men and women with the high-resolution manometry method for esophageal manometry, performed in the sitting position. The hypothesis was that men and women have differences in esophageal motility. Methods -High-resolution manometry was performed in normal volunteers, 10 men [mean age: 37.5 (8.1) years] and 12 women [mean age: 38.7 (7.5) years], in the sitting position and with 10 swallows of a 5 mL bolus of saline, with an interval of at least 30 seconds between consecutive swallows. We evaluated the integrated relaxation pressure of the lower esophageal sphincter, contraction front velocity, distal contraction integral, distal latency, proximal contraction extension, proximal contraction duration >30 mmHg, proximal contraction duration, proximal contraction integral and maximal upper esophageal sphincter pressure. Results -There was no significant difference between men and women in the variables measured. Conclusion -There was no difference in esophageal motility of men and women evaluated by the high resolution manometry method, in the sitting position with swallows of a liquid bolus. HEADINGS -Gastrointestinal motility. Manometry, methods. Sex factors.

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Section: Author' Contributionsunclassified

Section: Introductionmentioning

confidence: 99%

Esophageal Motility in Men and Women Evaluated by High-Resolution Manometry

Costa

Dantas

2017

Arq. Gastroenterol.

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“…We observed previously a difference between women and men in the contractility of the distal esophageal body (6) , which exclusively contains smooth muscle (14) . In this paper we described similar results in the proximal esophageal body, where there is striated muscle in the cranial part of both longitudinal and circular muscle layers that is gradually replaced by smooth muscle cells caudally (14) .…”

Section: -Out/dez 2009mentioning

confidence: 86%

“…Identidade de gênero. oropharyngeal transit (9) , UES opening duration (17,22) , pressure duration in the oropharynx with swallows (19) , duration of distal esophageal contractions (6) , and gastric emptying of solid food (13,15) . These results showed that women have a longer transit, contraction duration, UES opening and gastric emptying than men.…”

Section: -Out/dez 2009mentioning

confidence: 99%

“…Women have a longer duration of upper esophageal sphincter (UES) opening (17,22) , longer pressure duration in the oropharynx (19) and longer duration of esophageal contraction in the distal esophageal body (6) than men. These results suggest that women have a different response to wet swallows in the proximal digestive tract compared to men.…”

Section: Introductionmentioning

confidence: 99%

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Gender differences in proximal esophageal contractions

Dantas

Alves

Cassiani

2009

Arq. Gastroenterol.

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-Context -There are reports showing that gender has an influence on swallowing and on the contractions of the distal esophageal body. Objective -In this investigation we studied the effect of gender on proximal esophageal contraction. Methods -We studied 20 men (22-68 years old, median 39 years) and 44 women (18-61 years old, median 41 years) without symptoms and without gastrointestinal or respiratory diseases. We measured the time interval between the onset of pharyngeal contraction 1 cm proximal to the upper esophageal sphincter and the onset of the proximal esophageal contraction 5 cm from the pharyngeal recording. We also measured the amplitude, duration and area under the curve of the proximal esophageal contractions. The recording was performed by the manometric method with continuous perfusion. The contractions were recorded in duplicate after swallows of a 5 mL bolus of water. Results -There were no differences between men and women in the interval between the onset of pharyngeal and of esophageal contractions or in the amplitude of esophageal contractions. The duration of contractions was longer in women (2.35 ± 0.60 s) than in men (2.07 ± 0.62 s) but the difference did not reach statistical significance (P = 0.087). The area under the curve of the esophageal contraction was higher in women (130.2 ± 55.2 mm Hg x s) than in men (97.4 ± 49.4 mm Hg x s, P = 0.026). Conclusion -We conclude that there is a difference between men and women in the proximal esophageal contractions in response to wet swallows, although this difference is of no clinical relevance.

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Influence of Esophageal Motility on Esophageal Speech of Laryngectomized Patients

et al. 2002

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After laryngectomy for treatment of cancer of the larynx, the patient may have vocal rehabilitation by esophageal speech. Some patients fail to achieve the esophageal speech due to reasons involving surgery, radiotherapy, and psychological alterations. Our hypothesis is that the esophageal motility alterations consequent to laryngectomy may be involved in the failure to achieve esophageal speech. Using manometry with continuous perfusion, we studied the esophageal motility of 25 laryngectomized patients, 10 of them able to produce esophageal speech and 15 unable to produce esophageal speech, and 40 asymptomatic normal volunteers. The lower esophageal sphincter (LES) pressure was measured by the rapid pull-through method and the upper esophageal sphincter (UES) pressure by the station pull-through method. The contractions were measured at 5, 10, and 15 cm above the LES after the subjects performed 10 swallows with a 5-mL bolus of water. By comparing volunteers and laryngectomized patients, we found a lower UES pressure, lower amplitude of contractions, and increased percentage of simultaneous contractions in laryngectomized patients (p < 0.05). There was no difference between patients able and unable to produce esophageal speech in LES and UES pressure, esophageal contraction duration and velocity, or in the percentage of failed and simultaneous contractions. The esophageal contraction amplitude was lower in patients who acquired esophageal speech than in patients who did not (p < 0.05 at 10 cm from LES). We conclude that there are esophageal motility alterations in laryngectomized patients but only the decrease of esophageal contraction amplitude seems to be associated with the acquisition of esophageal speech.

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Gender effects on esophageal motility

Cited by 33 publications

References 13 publications

Esophageal Motility in Men and Women Evaluated by High-Resolution Manometry

Esophageal Motility in Men and Women Evaluated by High-Resolution Manometry

Gender differences in proximal esophageal contractions

Influence of Esophageal Motility on Esophageal Speech of Laryngectomized Patients

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