Aim. To assess the attitudes toward smoking in economically active men and women in Tyumen city within various education and family status. Material and methods. A singlepoint epidemiological study conducted, under the cardiological screening of open city population aged 2564 y. o., males 850 (respond 85,0%), females 704 (respond 70,4%). The attitudes toward smoking were assessed by the coverage method of selfcompletion of the WHO questionnaire "Knowledge and attitude of the one's health" with the preformulated points. Social status was assessed by educational level-elementary, general, graduate, and family status-with or none partner. Statistics was done with the software SPSS (11.5), Statistica 7.0 and Microsoft Excel. Values of p<0,05 were taken as significant. Results. The prevalence of smoking was higher in women having partner-17,0%, and in men with no partner-63,4%. Men with general education and partner significantly more frequently quit smoking than single men-23,7% and 13,6% (p<0,05; χ 2 =4,28, df=1, p=0,04). Same tendency was found in graduate women (p=0,07). Men with partner and general education significantly more commonly did not smoke during the year (p<0,05), and such tendency was found in graduate men. In women with general education and partner, during the year, less number smoked (p=0,08), χ 2 =2,91, df=1), but the intensity of smoking decreased (p=0,02, χ 2 =4,93, df=1) compared to single females. Conclusion. By the data from open city population, there are significant differences in attitudes of men and women toward tobacco smoking; there are different vectors of smoking tendency in relation with family status and education level.