Gender disparity in a cohort of stroke patients with incidence of obstructive sleep apnea

Edrissi, Camron; Rathfoot, Chase; Knisely, Krista; Sanders, Carolyn Breauna; Poupore, Nicolas; Nathaniel, Thomas I.

doi:10.1016/j.jvn.2021.10.002

Cited by 3 publications

(1 citation statement)

References 54 publications

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“…The probability of higher stroke severity is reported to be greater in patients with a score of >7 (more than 60.0%) than with a score of ≤7 (14.8%) [15]. A sharp difference and a lower severity was also observed at a threshold of ≤7 [16,17]. Therefore, understanding the risk factors contributing to stroke severity may help determine the characteristics of patients likely to show neurological changes during the first 48 h after the onset of AIS, especially in the older patient population.…”

Section: Introductionmentioning

confidence: 99%

Age Stratification in Acute Ischemic Stroke Patients with Heart Failure

Edrissi

Rathfoot

Knisely

et al. 2022

JCM

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Background and Purpose. Heart failure (HF) is considered one of the major risk factors associated with the severity of acute ischemic stroke(AIS). The risk factors associated with stroke severity in AIS with a history of HF is not fully understood. Methods. A prospectively maintained database from comprehensive stroke centers in PRISMA Health Upstate Sc, was analyzed for patients with AIS and a history of HF from January 2010 to 30 June 2016. The primary outcome was risk factors associated with a National Institute of Health Stroke Scale score (NIHSS) < 7 indicating lower severity and a score ≥ 7 indicating high severity for 65–74 age category and ≥75 years age category for AIS-HF patients. Univariate analysis was used to determine risk factors based on age categories and stroke severities, while multivariable analysis was used to adjust for the effect of confounding variables. Results: A total 367 AIS-HF patients were identified in this study, 113 patients were between 65–74 years old, while 254 patients were in the ≥75 years old age category. In the adjusted analysis for 65–74 age category, history of smoking (OR = 0.105, 95% Confidence interval (CI): 0.018–0.614, p = 0.012), triglycerides (Odd ratio(OR) = 0.993, 95% (CI): 0.987–0.999, p = 0.019), and International Normalized Ratio (INR) (OR = 0.454, 95% CI: 0.196–1.050, p = 0.045), and direct admission treatment (OR = 0.355, 95% CI: 0.137–0.920, p = 0.033) were associated with a lower stroke severity, elevated heart rate (OR = 1.032, 95% CI: 1.009–1.057, p = 0.007) was associated with a higher stroke severity. For the ≥75 years old age category, previous stroke (OR = 2.297, 95% CI: 1.171–9.852, p = 0.024), peripheral vascular disease (OR = 6.784, 95% CI: 1.242–37.065, p = 0.027), heart rate (OR = 1.035, 95% CI: 1.008–1.063, p = 0.012), and systolic blood pressure (OR = 1.023, 95% CI: 1.005–1.041, p = 0.012) were associated with a higher severe stroke severity. Conclusions: After adjusting for the effect of potential confounders, more risk factors were associated with a high severity of stroke among ≥75 years old compared with 65–74 years old AIS-HF patients. Elevated heart rate was an independent risk factor associated with stroke severity in 65–74 and ≥75 years old AIS-HF patients. Elevated heart rate and other identified risk factors should be managed to reduce stroke severity among elderly AIS-HF patients.

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Section: Introductionmentioning

confidence: 99%

Age Stratification in Acute Ischemic Stroke Patients with Heart Failure

Edrissi

Rathfoot

Knisely

et al. 2022

JCM

Self Cite

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Retrospective analysis of comorbidities in stroke patients with a history of obstructive sleep apnea treated with thrombolytic therapy

Knisely

Sanders

Edrissi

et al. 2022

Journal of Vascular Nursing

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Analysis of Severity in Ischemic Stroke Patients With Coronary Artery Disease in the Telestroke Network

et al. 2022

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Aim: This study investigated demographic and clinical risk factors associated with severity in acute ischemic stroke (AIS) patients with a history of coronary artery disease (CAD). Materials & methods: Multivariate logistic regression models were used to determine specific factors associated with worsening or improving neurologic functions among AIS patients with CAD treated in the telestroke. Results: AIS patients with CAD, peripheral vascular disease (OR: 3.995; 95% CI: 1.035–15.413; p = 0.044) and hypertension (OR: 6.056; 95% CI: 1.207–30.374; p = 0.029) were associated with worsening neurologic functions. Conclusion: Our findings suggest the need to develop strategic management to improve the care of AIS patients with a history of CAD that present with hypertension and peripheral vascular disease in the telestroke network.

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Gender disparity in a cohort of stroke patients with incidence of obstructive sleep apnea

Cited by 3 publications

References 54 publications

Age Stratification in Acute Ischemic Stroke Patients with Heart Failure

Age Stratification in Acute Ischemic Stroke Patients with Heart Failure

Retrospective analysis of comorbidities in stroke patients with a history of obstructive sleep apnea treated with thrombolytic therapy

Analysis of Severity in Ischemic Stroke Patients With Coronary Artery Disease in the Telestroke Network

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