Gender differences on chest pain perception associated with acute myocardial infarction in Chinese patients: a questionnaire survey

Khan, Jane J B; Albarran, John; Lopez, Violet

doi:10.1111/j.1365-2702.2010.03276.x

Cited by 15 publications

(17 citation statements)

References 50 publications

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“…Participants in our study also incorrectly expected a very high intensity of discomfort. In fact, the chest pain intensity was reported to range from 2 to 10 (on a 0–10-point scale) among local patients with AMI,23 indicating the possibility of mild pain. A false expectation of high-intensity discomfort (scoring at least 8/10) might lead to a longer delay in seeking treatment.…”

Section: Discussionmentioning

confidence: 99%

Low level of knowledge of heart attack symptoms and inappropriate anticipated treatment-seeking behaviour among older Chinese: a cross-sectional survey

Chau

Moe

Lee

et al. 2018

J Epidemiol Community Health

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Section: Discussionmentioning

confidence: 99%

Low level of knowledge of heart attack symptoms and inappropriate anticipated treatment-seeking behaviour among older Chinese: a cross-sectional survey

Chau

Moe

Lee

et al. 2018

J Epidemiol Community Health

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“…Interestingly, in patients reporting chest pain, pain intensity did not differ between genders, despite the wide variety of underlying diseases. In studies on acute myocardial infarction, however, higher pain intensity scores have been reported by men [24] , while in studies enrolling patients with angina, acute myocardial infarction or chest pain, higher pain intensity is reported mostly by women [4,25,26] . Hence, gender disparities in pain perception seem to vary according to the underlying disease.…”

Section: Discussionmentioning

confidence: 99%

Gender-Related Differences in Patients Presenting with Suspected Acute Coronary Syndromes: Clinical Presentation, Biomarkers and Diagnosis

et al. 2015

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Objectives: Gender differences in patients presenting with suspected acute coronary syndromes (ACS) have not yet been fully characterized. The aim of this study was to assess gender-related disparities in clinical profiles, biomarkers and diagnoses of patients with suspected ACS. Methods: This singlecentre, prospective cohort study included 377 consecutive patients presenting with suspected ACS to the emergency department. Suspected ACS was defined as a request for conventional troponin T (c-cTnT) measurements on clinical grounds. Results: Women were older than men (p = 0.004), and had a lower prevalence of known coronary artery and peripheral vascular disease (p < 0.05). c-cTnT was positive in 8% of female and in 14% of male patients (p = 0.16), TIMI risk score and cardiac biomarkers including c-cTnT, hs-cTnT, myoglobin, creatine kinase, N-terminal pro-brain natriuretic peptide, myeloid-related protein 8/14 and pregnancy-associated plasma protein A were lower in women (p < 0.05). Women were less frequently diagnosed with ACS (30 vs. 51%), and were not referred for urgent coronary angiography as often as men (p < 0.001). In multivariate analysis, female gender was associated with a lower referral for coronary angiography (HR 0.41, 95% CI 0.23-0.78, p = 0.006). Conclusions: In patients with suspected ACS, women presented with different biomarker profiles, and were less often diagnosed with ACS and referred to coronary angiography. angiography as often as men (p < 0.001). In multivariate analysis, female gender was associated with a lower referral for coronary angiography (HR 0.41, 95% CI 0.23-0.78, p = 0.006). Conclusions:In patients with suspected ACS, women presented with different biomarker profiles, and were less often diagnosed with ACS and referred to coronary angiography.

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“…Khan et al, (2010) found no gender differences in chest pain intensity. They found that women experience more radiation of pain to the back of neck, upper abdomen and back.…”

Section: Symptom Presentationmentioning

confidence: 58%

“…They found that women experience more radiation of pain to the back of neck, upper abdomen and back. Female patients were more likely to be misdiagnosed, to receive suboptimal care and have higher mortality rates (Khan et al, 2010 1947 ACS patients were enrolled in the study of which 545 (28%) were women. The female participants were also significantly older than the male participants (p<.001).…”

Section: Symptom Presentationmentioning

confidence: 99%

Disparities Between Men and Women in the Time of Initial EKG Acquisition

McGillivray

2015

Preprint

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Cardiovascular disease is the most common cause of death around the world.Initial treatment is often time dependent. An EKG is the single most important initial clinical test to diagnose acute myocardial infarctions. Recognizing acute coronary symptoms in the initial presentation to an emergency department is critical in order to obtain the initial EKG. Of concern is the likelihood of delay in the initial EKG acquisition for females. The purpose of the research study was to distinguish if there is a disparity between genders to the best practice of door to EKG in 10 minutes from the arrival time in the Emergency department. A retrospective chart review was conducted with a total of 60 charts consisting of 30 females and 30 males who experienced an AMI.The time of initial arrival to the ED and initial EKG acquisition were compared. Results demonstrated that the initial EKG acquisition was shorter for males, average of 15 minutes as compared to females, average of 18 minutes. The data also demonstrated that only 32% (n=19) of patients had an initial EKG in 10 minutes or less and 68% (n=41) in greater than 10 minutes. Average age of females was 72 compared to males at 62. Thirty seven percent (n=22) of the patients presented with a chief complaint other than chest pain. Further research is indicated to determine reasons for delay in initial EKG acquisition between genders.

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Gender differences on chest pain perception associated with acute myocardial infarction in Chinese patients: a questionnaire survey

Abstract: Irrespective of culture, women with myocardial infarction tend to present with atypical chest pain symptoms and therefore they should be aggressively investigated.

Cited by 15 publications

References 50 publications

Low level of knowledge of heart attack symptoms and inappropriate anticipated treatment-seeking behaviour among older Chinese: a cross-sectional survey

Low level of knowledge of heart attack symptoms and inappropriate anticipated treatment-seeking behaviour among older Chinese: a cross-sectional survey

Gender-Related Differences in Patients Presenting with Suspected Acute Coronary Syndromes: Clinical Presentation, Biomarkers and Diagnosis

Disparities Between Men and Women in the Time of Initial EKG Acquisition

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