2013
DOI: 10.1016/j.jaci.2012.09.024
|View full text |Cite
|
Sign up to set email alerts
|

Gender differences in the bronchoalveolar lavage cell proteome of patients with chronic obstructive pulmonary disease

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

8
74
0

Year Published

2013
2013
2023
2023

Publication Types

Select...
8

Relationship

3
5

Authors

Journals

citations
Cited by 63 publications
(84 citation statements)
references
References 53 publications
8
74
0
Order By: Relevance
“…We also investigated the gene expression profile of bronchial epithelial cells in bronchial brush biopsies harvested from healthy subjects by selecting data of interest from a broad mRNA analyses of the COSMIC cohort material (22,23). Here, we found that these bronchial epithelial cells contain mRNA for IL26, TLR3, TLR7 and TLR8 among others ( Figure 6A), which are compatible with our finding on primary bronchial epithelial cells in vitro.…”
Section: Interleukin-26 and Its Archetype Signaling Responses In Bronsupporting
confidence: 85%
See 2 more Smart Citations
“…We also investigated the gene expression profile of bronchial epithelial cells in bronchial brush biopsies harvested from healthy subjects by selecting data of interest from a broad mRNA analyses of the COSMIC cohort material (22,23). Here, we found that these bronchial epithelial cells contain mRNA for IL26, TLR3, TLR7 and TLR8 among others ( Figure 6A), which are compatible with our finding on primary bronchial epithelial cells in vitro.…”
Section: Interleukin-26 and Its Archetype Signaling Responses In Bronsupporting
confidence: 85%
“…The data (raw signals) were presented as relative fluorescence units (RFU). Here, 10 randomly selected bronchial brush biopsy samples from the human (4 male and 6 female) donors were selected from the pool of the COSMIC cohort (22,23). The analyses of mRNA were then performed on the cells in the bronchial brush biopsy samples as previously described (27).…”
Section: Cell Culture and Stimulationmentioning
confidence: 99%
See 1 more Smart Citation
“…As a control group, healthy age-matched never smokers and current smokers with normal lung function from the Karolinska COPD and Smoking from an OMIC Perspective (COSMIC) cohort was used16 consisting of 79 healthy volunteers who underwent bronchoscopy and BAL. Another 15 individuals served as a control group for comparison of biopsies.…”
Section: Methodsmentioning
confidence: 99%
“…Improvements to the two-dimensional gel electrophoresis in the form of differential protein labelling with multiple dyes has recently emphasised the utility of the two-dimensional gel technique for finding biomarkers of lung diseases in challenging biofluids such as sputum [69]. KOHLER et al [70] recently utililised multiplexed differential gel electrophoresis to identify a female-dominated subphenotype of COPD. In this study, a subset of 19 proteins in alveolar macrophages primarily originating from the lysosomal activity and oxidative phosphorylation pathways were found to provide classification of female COPD patients with 78% predictive power.…”
Section: Proteomicsmentioning
confidence: 99%