“…In our preliminary regression analyses, QOL was found to differ by sex; males had lower scores in the psychological and social relationships domains than their female counterparts. While these findings seem to be in direct contradiction with studies demonstrating the opposite pattern (Dubreucq, Plasse, Gabayet, et al, 2021;Teh et al, 2008), or no pattern at all (Rotstein et al, 2022;Shafie et al, 2021), a plausible explanation for this discrepancy is one that takes sex differences in premorbid functioning into account. Compared to females, males have been shown to have lower levels of premorbid functioning (Rabinowitz et al, 2002), which is defined as 'social, interpersonal, school and work functioning in the period before the onset of psychosis' (Addington & Addington, 2005), and adjustment (Preston et al, 2002).…”