Gender differences in narcotic-induced emesis in the ED

Zun, Leslie S.; Downey, La Vonne A.; Gossman, William G.; Rosenbaum, Jason; Sussman, Glen

doi:10.1053/ajem.2002.32631

Cited by 53 publications

(36 citation statements)

References 13 publications

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“…This finding is in agreement with the results of other studies. [10][11][12] Clinicians need to be alert to the greater risk of opioid-induced nausea or vomiting among women.…”

Section: Discussionmentioning

confidence: 99%

Predictive Factors for Nausea or Vomiting in Patients with Cancer Who Receive Oral Oxycodone for the First Time: Is Prophylactic Medication for Prevention of Opioid-Induced Nausea or Vomiting Necessary?

Kanbayashi

Hosokawa

2014

Journal of Palliative Medicine

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“…This finding is in agreement with the results of other studies. [10][11][12] Clinicians need to be alert to the greater risk of opioid-induced nausea or vomiting among women.…”

Section: Discussionmentioning

confidence: 99%

Predictive Factors for Nausea or Vomiting in Patients with Cancer Who Receive Oral Oxycodone for the First Time: Is Prophylactic Medication for Prevention of Opioid-Induced Nausea or Vomiting Necessary?

Kanbayashi

Hosokawa

2014

Journal of Palliative Medicine

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“…Because some evidence suggests that opioid side effects might be sex dependent, 39,41 we also examined sex differences in the adverse effects of morphine in our sample. In addition, we determined the sex-related impact of morphine on baseline cardiovascular responses as well as cardiovascular reactivity to the ischemic pain task.…”

mentioning

confidence: 99%

“…More directly relevant is a study of narcotic-induced emesis in the emergency department. 41 These authors reported that among 325 patients receiving narcotics (morphine 54.5%, meperidine 24.3%) for pain at a Level I trauma …”

mentioning

confidence: 99%

Morphine responses and experimental pain: Sex differences in side effects and cardiovascular responses but not analgesia

Fillingim¹,

Ness²,

Glover³

et al. 2005

The Journal of Pain

148

127

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“…It should be noted that findings from several studies suggest that sex (19)(20)(21)(22)(23)(24) and ethnic (25-28) differences exist in the prevalence and severity of side effects. For example, women were found to be more sensitive to the respiratory effects of morphine (22).…”

Section: Discussionmentioning

confidence: 99%

Differences in the Prevalence and Severity of Side Effects Based on Type of Analgesic Prescription in Patients with Chronic Cancer Pain

Villars

Dodd

West

et al. 2007

Journal of Pain and Symptom Management

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An understanding of the relationship between the type of analgesic prescription and the prevalence and severity of side effects is crucial in making appropriate treatment decisions. The purposes of this study were: to determine if there were differences in the prevalence of side effects among four different types of analgesic prescriptions (i.e., no opioid, only an as needed (PRN) opioid, only an around-the-clock (ATC) opioid, or an ATC + PRN opioid); to determine if there were differences in the severity of side effects among the four prescriptions groups; and to determine the relationships between the total dose of opioid analgesic medication prescribed and taken and the severity of side effects. As part of a larger study, 174 cancer patients with bone metastasis reported their analgesic use and the prevalence and severity of eleven side effects. Significant differences (P < 0.05) were found in prevalence rates for seven of the side effects among the four prescription groups. The highest prevalence rates were found in the only ATC and ATC + PRN groups. Significant differences were found in the severity scores for five of the side effects, with the highest severity scores reported by patients in the only ATC and ATC + PRN groups. Significant positive correlations were found between the severity of six of the side effects and the total dose of opioid prescribed and taken. Risk factors for analgesic-induced side effects are ATC and ATC + PRN prescription types and higher doses of opioid analgesics.

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Gender differences in narcotic-induced emesis in the ED

Cited by 53 publications

References 13 publications

Predictive Factors for Nausea or Vomiting in Patients with Cancer Who Receive Oral Oxycodone for the First Time: Is Prophylactic Medication for Prevention of Opioid-Induced Nausea or Vomiting Necessary?

Predictive Factors for Nausea or Vomiting in Patients with Cancer Who Receive Oral Oxycodone for the First Time: Is Prophylactic Medication for Prevention of Opioid-Induced Nausea or Vomiting Necessary?

Morphine responses and experimental pain: Sex differences in side effects and cardiovascular responses but not analgesia

Differences in the Prevalence and Severity of Side Effects Based on Type of Analgesic Prescription in Patients with Chronic Cancer Pain

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