Gender Differences in Lifetime Alcohol Dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions

Khan, Sharaf S.; Okuda, Mayumi; Hasin, Deborah S.; Villa, Roberto Secades; Keyes, Katherine M.; Lin, Keng-Han; Grant, Bridget F.; Blanco, Carlos

doi:10.1111/acer.12158

Cited by 95 publications

(81 citation statements)

References 46 publications

(66 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For clarity, the plot shows only a random 10% of the data at each age. Consistent with previous research, this figure illustrates the sex difference in drinking behaviors (Khan et al, 2013), as well as the peak in drinking during the early 20s (Schulenberg et al, 1996). A visual inspection of the scatter plot of parental drinking index scores versus offspring scores indicates a linear relationship.…”

Section: Descriptive Resultssupporting

confidence: 87%

Parent–Offspring Resemblance for Drinking Behaviors in a Longitudinal Twin Sample

Saunders

Iacono

Elkins

2017

J. Stud. Alcohol Drugs

View full text Add to dashboard Cite

ABSTRACT. Objective:The purpose of the current study was to evaluate parent-offspring resemblance for alcohol consumption and dependence symptoms, including sex-specific effects, and how these patterns change across adolescence and early adulthood. Method: Three cohorts of twins were assessed longitudinally at five time points between ages 14 and 29 years, with parents directly assessed at intake, using structured interviews. Twin offspring and parents from the population-based Minnesota Twin Family Study were included for a total sample size of 3,762 offspring (52% female) and their parents. Alcohol use was measured using an index based on drinking quantity, frequency, maximum drinks, and number of intoxications. Alcohol dependence symptom counts were also used. Results: Parent-offspring correlations for alcohol consumption increased from age 14 (r = .12) to age 17 (r = .25), remained stable from ages 17 through 24, and then decreased slightly by age 29 (r = .19). Familial resemblance for symptoms of alcohol dependence peaked at age 17 (r = .18) then decreased through age 29 (r = .11). Parent-offspring correlations of both measures did not vary significantly by sex of offspring or sex of parent. Conclusions: Overall, parent-offspring resemblance for alcohol use and problems is relatively stable after early adulthood, with resemblance for alcohol use at higher magnitudes across offspring development. Evidence for differential resemblance based on sex of offspring or parents was lacking. (J. Stud. Alcohol Drugs, 78, 49-58, 2017)

show abstract

Section: Descriptive Resultssupporting

confidence: 87%

Parent–Offspring Resemblance for Drinking Behaviors in a Longitudinal Twin Sample

Saunders

Iacono

Elkins

2017

J. Stud. Alcohol Drugs

View full text Add to dashboard Cite

show abstract

“…Surprisingly few papers focused on young adults [226,227]; those that did also found comorbidity. Regardless of the focal disorder or symptom of the paper, studies addressing gender generally found greater internalizing comorbidity in women and externalizing comorbidity in men [57,61,67,68,228-230]. …”

Section: Major Findingsmentioning

confidence: 99%

The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 and 2: review and summary of findings

Hasin

Grant

2015

Soc Psychiatry Psychiatr Epidemiol

Self Cite

386

293

View full text Add to dashboard Cite

Purpose The NESARC, a “third generation” psychiatric epidemiologic survey that integrated detailed measures of alcohol and drug use and problems, has been the data source for over >850 publications. A comprehensive review of NESARC findings and their implications is lacking. Method NESARC was a survey of 43,093 participants that covered alcohol, drug and psychiatric disorders, risk factors, and consequences. Wave 1 of the NESARC was conducted in 2001-2002. Three years later, Wave 2 follow-up re-interviews were conducted with 34,653 of the original participants. Scopus and Pubmed were used to search for NESARC papers, which were sorted into topic areas and summarized. Result The most common disorders were alcohol and post-traumatic stress disorders, and major depression. Females had more internalizing disorders and males had more externalizing disorders, although the preponderance of males with alcohol disorders (the “gender gap”) is less pronounced than it was in previous decades. A race/ethnic “paradox” (lower risk among disadvantaged minorities than whites) remains unexplained. Younger participants had higher risk for substance and personality disorders, but not unipolar depressive or anxiety disorders. Psychiatric comorbidity was extensive and often formed latent trans-diagnostic domains. Since 1991-1992, risk for marijuana and prescription drug disorders increased, while smoking decreased, although smoking decreases were less pronounced among those with comorbidity. A nexus of comorbidity, social support, and stress predicted transitions in diagnostic status between Waves 1 and 2. Childhood maltreatment predicted psychopathology. Alcohol and drug use disorders were seldom treated; attitudinal barriers (little perceived need, perceived alcoholism stigma, pessimism about efficacy) were more important in predicting non-treatment than financial barriers. Conclusions Understanding comorbidity and the effects of early stressors will require research incorporating biologic components, e.g., genetic variants and brain imaging. The lack of treatment for alcohol and drug disorders, predicted by attitudinal rather than financial variables, suggests urgent need for public and professional education to reduce the stigma associated with these disorders, and increase knowledge of treatment options.

show abstract

“…1 Historically, the prevalence of alcohol use and related harms has been between 2 and 12 times higher in men than women. [2][3][4][5][6][7] However, there is emerging evidence to suggest that the gap between men and women in alcohol use and related harms is closing among recently born cohorts. [8][9][10][11] Understanding sex-specific birth cohort trends in the epidemiology of alcohol use is vital as they point to key environmental and social mechanisms associated with population shifts in alcohol use patterns.…”

mentioning

confidence: 99%

Birth cohort trends in the global epidemiology of alcohol use and alcohol-related harms in men and women: systematic review and metaregression

et al. 2016

Self Cite

View full text Add to dashboard Cite

Objective: Historically, alcohol use and related harms are more prevalent in men than in women. However, emerging evidence suggests the epidemiology of alcohol use is changing in younger cohorts. The current study aimed to systematically summarise published literature on birth cohort changes in male-tofemale ratios in indicators of alcohol use and related harms. Methods:We identified 68 studies that met inclusion criteria. We calculated male-to-female ratios for 3 broad categories of alcohol use and harms (any alcohol use, problematic alcohol use and alcoholrelated harms) stratified by 5-year birth cohorts ranging from 1891 to 2001, generating 1568 sex ratios. Random-effects meta-analyses produced pooled sex ratios within these 3 categories separately for each birth cohort.Findings: There was a linear decrease over time in the sex ratio for all 3 categories of alcohol use and related harms. Among those born in the early 1900s, males were 2.2 (95% CI 1.9 to 2.5) times more likely than females to consume alcohol, 3.0 (95% CI 1.5 to 6.0) times more likely to drink alcohol in ways suggestive of problematic use and 3.6 (95% CI 0.4 to 30.3) times more likely to experience alcohol-related harms. Among cohorts born in the late 1900s, males were 1.1 (95% CI 1.1 to 1.2) times more likely than females to consume alcohol, 1.2 (95% CI 1.1 to 1.4) times more likely to drink alcohol in ways suggestive of problematic use and 1.3 (95% CI 1.2 to 1.3) times more likely to experience alcohol-related harms.Conclusions: Findings confirm the closing malefemale gap in indicators of alcohol use and related harms. The closing male-female gap is most evident among young adults, highlighting the importance of prospectively tracking young male and female cohorts as they age into their 30s, 40s and beyond.Alcohol use and alcohol-related harms are among the most significant risk factors for burden of disease. Overall, they resulted in around 5 million deaths globally in 2010, and were responsible for more than 161 million years of life lost, equating to 5% of total global health burden.1 Historically, the prevalence of alcohol use and related harms has been between 2 and 12 times higher in men than women.2-7 However, there is emerging evidence to suggest that the gap between men and women in alcohol use and related harms is closing among recently born cohorts. [8][9][10][11] Understanding sex-specific birth cohort trends in the epidemiology of alcohol use is vital as they point to key environmental and social mechanisms associated with population shifts in alcohol use patterns. For example, studies have attributed these generational shifts in sex-specific drinking to changes in traditional gender roles over Strengths and limitations of this study ▪ Prior to this study, the evidence around gender convergence in alcohol use and alcohol-related harms was fragmented. This study systematically summarised all available literature and provided a quantification of the rate of gender convergence through the derivation of a single metric -the m...

show abstract

Gender Differences in Lifetime Alcohol Dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions

Cited by 95 publications

References 46 publications

Parent–Offspring Resemblance for Drinking Behaviors in a Longitudinal Twin Sample

Parent–Offspring Resemblance for Drinking Behaviors in a Longitudinal Twin Sample

The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 and 2: review and summary of findings

Birth cohort trends in the global epidemiology of alcohol use and alcohol-related harms in men and women: systematic review and metaregression

Contact Info

Product

Resources

About