Gender differences in factor structure of the Self-Administered Alcoholism Screening Test

Lm, Allen; Cj, Nelson; Rouhbakhsh, Poupak; Sl, Scifres; Rl, Greene; St, Kordinak; Davis, Lisa M.; Rm, Morse

doi:10.1002/(sici)1097-4679(199806)54:4<439::aid-jclp6>3.0.co;2-i

Cited by 19 publications

(8 citation statements)

References 5 publications

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“…Studies have shown the ratio of male to female users of alcohol is 1.3 ( Sadock, Sadock, & Ruiz, 2000 ). This result conforms to those we have found and to those from other researches carried out in Iran ( Allen et al, 1998 ). The lower frequency of alcohol use in women may rely on various reasons, possibly cultural, social, and religious.…”

Section: Discussionsupporting

confidence: 93%

Alcohol Abuse and Suicide Attempt in Iran: A Case-Crossover Study

Ghanbari¹,

Malakouti²,

Nojomi³

et al. 2015

GJHS

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Alcohol use and its disorders are associated with increased risk of suicidal behaviors Research has shown that 6-8% of those who use alcohol have a history of suicide attempt. Given the prohibition of alcohol use legally, the increased alcohol consumption, and the lack of strong evidence in favor of its use associated with suicide in Iran, this study was conducted to determine the link between suicide attempt and alcohol abuse. The case-crossover method was used in this research. Out of 305 referrals to the emergency room due to a suicide attempt, 100 reported drinking alcohol up to six hours before their attempt. Paired Matching and Usual Frequency were employed to analyze the data with STATA 12.0. The probability of attempting suicide up to six hours after drinking alcohol appeared increased by 27 times (95% CI: 8.1-60.4). Separate analysis for each of these hours from the first to the sixth hour after alcohol use was also performed. Fifty percent of attempted suicides happened one hour after alcohol use. Relative risk for the first and second hour was 10% and 5% respectively. Alcohol use is a strong proximal risk factor for attempted suicide among Iranian subjects. Prevention of alcohol use should be considered in setting up of the national Suicide attempt prevention program.

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Section: Discussionsupporting

confidence: 93%

Alcohol Abuse and Suicide Attempt in Iran: A Case-Crossover Study

Ghanbari¹,

Malakouti²,

Nojomi³

et al. 2015

GJHS

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“…PCA and factor analysis are the most widely used statistical methods to reduce the number of dimensions in data analysis and to investigate multiple intercorrelations between variables. [13][14][15]18 It has also been used to define similar and deviating responses among biological data (variables). [19][20][21][22][23] Results of the multiple intercorrelation analysis of the data in Table 1 are displayed in Table 2A (correlation matrix) and Table 2B (factor loadings of the 7 variables).…”

Section: Statistical Comparison Of the Results Of The Mtt Atp And Calcein Assaysmentioning

confidence: 99%

“…The data matrix that contains pIC 50 values (= -logIC 50 ) was analyzed by principal component analysis. [13][14][15] In contrast to previously published articles, which compared 2 parameters only, 12,16 the principal component analysis applied here allows to directly compare more than 2 variables, namely, data of the MTT, ATP, and calcein assays in the 3 different cell lines.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Usefulness of the MTT, ATP, and Calcein Assays to Predict the Potency of Cytotoxic Agents in Various Human Cancer Cell Lines

Mueller¹,

Kassack²,

Wiese³

2004

SLAS Discovery

201

146

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Cell viability assays are important tools in oncological research and clinical practice to assess the tumor cell sensitivity of individual patients. The purpose of this study was to demonstrate the comparability of 3 widely used assays (MTT, ATP, calcein assays) by principal component analysis. The study included 4 different cytostatics (cisplatin, docetaxel, doxorubicin, vinblastine) and 3 different human cancer cell lines (MCF-7, A2780, doxorubicin resistant A2780adr). Ninety-three percent of the total variance of all variables included in the principal component analysis (resulting from 3 cell lines and 3 assays) could be explained by 1 principal component. Factor loadings were ≥ 0.937 except for the variable MTT-A2780adr, which was 0.872. These results indicate the similarity of the 3 assays. A 2nd principal component analysis included literature data and showed accordance of data from this study and the literature. The MTT assay was further improved as a high-throughput screening-capable assay. The ATP assay is able to detect effects of cytostatics already after 1 h incubation. The determination of resistance factors allowed to differentiate cytostatics into P-gp or non-P-gp substrates. In conclusion, this study provides improved microplate reader-based cell viability assays and sets a statistically solid basis for a future comparison of data obtained in different laboratories by any of the 3 assays. (Journal of Biomolecular Screening 2004:506-515)

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“…There was no SAAST‐R item for which females had a higher endorsement rate than males in either criterion group. In contrast, using the original SAAST, researchers had found female inpatients were more likely to endorse occupationally and socially disruptive behaviors, while male inpatients were more likely to endorse loss of control and report concern from others about their drinking 39,42 . They also found women were more likely than men to report emotional problems as a consequence of their drinking.…”

Section: Discussionmentioning

confidence: 95%

Validation of the Revised Self‐Administered Alcohol Screening Test (SAAST‐R)

et al. 2006

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This study examined the sensitivity and specificity of the revised Self-Administered Alcohol Screening Test (SAAST-R)1 among adult outpatients evaluated at community addictions and psychiatry and psychology clinics. A total of 417 adults (mean +/- SD age of 41.4 +/- 15.0 years, 52% female, 91% Caucasian) completed the 36-item SAAST-R prior to their evaluation. Based on the clinician's documentation of the patient's alcohol use, two criterion groups were established: one composed of subjects classified as having no alcohol problems (n = 214), and one with alcohol problems (n = 203). The SAAST-R was found to have high internal consistency reliability (Cronbach's alpha = 0.96), sensitivity (90%), and specificity (82%) for differentiating outpatients with and without alcohol problems, respectively, using a cut point of >or=4 to indicate risk for alcohol-related problems. The SAAST-R was found to have good sensitivity and specificity among both males and females.

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Gender differences in factor structure of the Self-Administered Alcoholism Screening Test

Cited by 19 publications

References 5 publications

Alcohol Abuse and Suicide Attempt in Iran: A Case-Crossover Study

Alcohol Abuse and Suicide Attempt in Iran: A Case-Crossover Study

Comparison of the Usefulness of the MTT, ATP, and Calcein Assays to Predict the Potency of Cytotoxic Agents in Various Human Cancer Cell Lines

Validation of the Revised Self‐Administered Alcohol Screening Test (SAAST‐R)

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