School bullying is a widespread issue with significant consequences for all individuals involved, including bullies, victims, and bystanders. Bystanders, who witness bullying situations, play a crucial role in intervention programs aiming to address this problem effectively. This review examines three interventions that specifically target bystanders, aiming to empower and train students to become defenders against bullying. The interventions discussed are the STAC program, the KiVa anti-bullying program, and the NoTrap! anti-bullying program. By focusing on equipping bystanders with effective strategies, these interventions aim to prevent and combat bullying incidents. This review discusses the development and effectiveness of these programs, emphasizing the importance of bystander perspectives in bullying prevention. Overall, empowering bystanders represents a promising strategy to prevent and combat bullying, and further research and intervention development from the bystander perspective are encouraged.