Gender Differences in Asthma-COPD Overlap and Associated Comorbid Conditions

Garneau-Picard, F.-A.; Boulay, Marie‐Ève; Boulet, L

doi:10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1471

Cited by 1 publication

(1 citation statement)

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“…Garneau-Picard et al 43 investigated the influence of smoking on multimorbidity in people with ACOS. In a group of 154 patients with irreversible airway obstruction (47% men, 53% women; 100 smokers with ACOS and 54 with irreversible airway obstruction not related to smoking), a sex-specific symptom pattern was found that suggested greater susceptibility of women to smoke.…”

Section: Resultsmentioning

confidence: 99%

Modifiable risk factors that may be addressed in routine care to prevent progression to and extension of multimorbidity in people with COPD: a systematic literature review

Orlowski,

Ettinger,

Bottle

et al. 2024

BMJ Open Resp Res

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Chronic obstructive pulmonary disease (COPD) is a multisystem disease, and many patients have multiple conditions. We explored multimorbidity patterns that might inform intervention planning to reduce health-care costs while preserving quality of life for patients. Literature searches up to February 2022 revealed 4419 clinical observational and comparative studies of risk factors for multimorbidity in people with COPD, pulmonary emphysema, or chronic bronchitis at baseline. Of these, 29 met the inclusion criteria for this review. Eight studies were cluster and network analyses, five were regression analyses, and 17 (in 16 papers) were other studies of specific conditions, physical activity and treatment. People with COPD more frequently had multimorbidity and had up to ten times the number of disorders of those without COPD. Disease combinations prominently featured cardiovascular and metabolic diseases, asthma, musculoskeletal and psychiatric disorders. An important risk factor for multimorbidity was low socioeconomic status. One study showed that many patients were receiving multiple drugs and had increased risk of adverse events, and that 10% of medications prescribed were inappropriate. Many patients with COPD have mainly preventable or modifiable multimorbidity. A proactive multidisciplinary approach to prevention and management could reduce the burden of care.

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Section: Resultsmentioning

confidence: 99%