Gender difference on the symptoms, health‐seeking behaviour, social impact and sleep quality in irritable bowel syndrome: a Rome II‐based survey in an apparent healthy adult Chinese population in Taiwan

Lu, Ching Liang; Chang, Full Young; Lang, Hui Chu; Chen, C.-Y.; Luo, Jiing‐Chyuan; Lee, Shin-Da

doi:10.1111/j.1365-2036.2005.02512.x

Cited by 38 publications

(37 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As in previous studies [2,3,22,24,32,37], other organic gastrointestinal diseases, such as gallbladder stones, peptic ulcers, and reflux esophagitis, were found in the IBS patients in the present study. However, there were no differences in the prevalence rates of these diseases between the IBS (+) and (À) groups.…”

Section: Discussionsupporting

confidence: 87%

See 1 more Smart Citation

A Survey about Irritable Bowel Syndrome in South Korea

et al. 2007

View full text Add to dashboard Cite

The aims of the present study were: (1) to assess the prevalence of symptom-based irritable bowel syndrome (IBS) in Korean adults, (2) to assess several organic abnormalities which can be found in IBS patients, and (3) to analyze the risk or associated factors that influence the presence of IBS. Adult health examinees were requested to fill out a questionnaire. The prevalence of IBS was calculated using Rome II criteria. Using several tests, several organic abnormalities were identified in the IBS group. Risk factors were analyzed by comparing the IBS and normal groups. The prevalence value for IBS according to Rome II criteria was 16.8%. Mucosal hyperplasia, lymphocyte aggregation, and increased eosinophil counts were relatively common microscopic findings in IBS group. Female gender, self-consciousness of IBS, and irregular defecation were expressed as significantly independent risk or associated factors for IBS. Several colonic microscopic findings mentioned above may be helpful in accurate diagnosis of IBS. Therefore a more-precise and large population study about these findings is necessary to reach a definitive conclusion.

show abstract

Section: Discussionsupporting

confidence: 87%

“…There are data that show differences in IBS prevalence according to gender, ethnicity, age, region, etc. [2,3,6,17,[22][23][24][29][30][31]. Therefore, these differences may result from real population differences.…”

Section: Discussionmentioning

confidence: 99%

A Survey about Irritable Bowel Syndrome in South Korea

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Moreover, in other studies conducted in Asian countries, including Korea, IBS was reported to occur in men more often than in women. [42][43][44] The reason for the discrepancy in the occurrence of IBS according to sex between Western and Asian countries is unclear but could be the result of cultural, psychosocial, or healthcare access issues, rather than purely sex-related physiologic differences. 45 The mechanism underlying the relationship between the SE type and IBS is unknown.…”

Section: Discussionmentioning

confidence: 99%

So-Eum Type as an Independent Risk Factor for Irritable Bowel Syndrome: A Population-Based Study in Korea

Lee

Yoon²,

Yi³

et al. 2014

The Journal of Alternative and Complementary Medicine

View full text Add to dashboard Cite

Objectives: It has been hypothesized that Sasang constitutional types (SCTs) have a specific hypoactive organ, which can account for vulnerability to related diseases or symptoms. This study examined the relationship between SCTs and irritable bowel syndrome (IBS). Design: Cross-sectional study in a population-based cohort study in Korea. Participants: 1362 individuals (705 men and 657 women) who participated in the Korean Genome and Epidemiology Study. Outcome measures: The participants were classified into SCTs by the integrated diagnostic model and asked about symptoms related to IBS using the Rome II criteria. Results: The prevalence of IBS differed significantly among the SCTs, with 33 (18.3%) of the So-eum (SE) type, 74 (9.9%) of the Tae-eum (TE) type, and 57 (13.2%) of the So-yang (SY) type having IBS. Even after adjustment for possible confounders, the SE type for both sexes continued to show 1.82-fold (95% confidence interval [CI], 1.05-3.16) excess odds of having IBS. Men with SE type had a 2.97 times (95% CI, 1.34-6.58) and a 2.50 times (95% CI, 1.15-5.47) significantly higher odds of having IBS than the TE and SY types, respectively. In analysis for the joint effect of SCT and psychological stress, the multivariate odds ratio of IBS was 3.21 (95% CI, 1.33-7.75) for the SE type and Psychological Well-Being Index-Short Form (PWI-SF) score ( < 27), and 5.83 (95% CI, 1.80-18.88) for the SE type and PWI-SF ( ‡ 27) compared with the TE type and PWI-SF score ( < 27). Conclusions: The SE type of SCT is an independent risk factor for IBS. The findings support the hypothesis that persons with SE type are vulnerable to gastrointestinal diseases.

show abstract

“…The reported IBS prevalence is determined by a number of factors including subject gender, used criteria, questionnaires, study methods, locations, geographical characters, cultural and social backgrounds, and ethnicity [3,8,9,11] . Clinically, IBS is not only confined to the colon but may also extend to other organs and systems since IBS individuals usually have multiple comorbidities such as dyspepsia, gastro-esophageal reflux disease, interstitial cystitis, fibromyalgia, chronic fatigue, insomnia, headache/migraine and psychiatric disturbances [12][13][14][15][16][17][18] . Owing to the commonly associated somatic comorbidities and high level of psychiatric disturbances, IBS subjects often have absenteeism, reduced quality of life (QoL) and multiple healthcare seeking behaviors, which lead to great social and economic burdens [13,16,[19][20][21] .…”

Section: Introductionmentioning

confidence: 99%

Irritable bowel syndrome: The evolution of multi-dimensional looking and multidisciplinary treatments

Chang¹

2014

WJG

View full text Add to dashboard Cite

Irritable bowel syndrome (IBS) is common in the society. Among the putative pathogeneses, gut dysmotility results in pain and disturbed defecation. The latter is probably caused by the effect of abnormal gut water secretion. The interaction between abnormal gas accumulation, abdominal pain and bloating remains controversial. Visceral hypersensitivity and its modification along with the central transmission are the characteristics of IBS patients. The identification of biologic markers based on genetic polymorphisms is undetermined. Imbalanced gut microbiota may alter epithelial permeability to activate nociceptive sensory pathways which in turn lead to IBS. Certain food constituents may exacerbate bowel symptoms. The impact of adult and childhood abuses on IBS is underestimated. Using the concept of biopsychosocial dysfunction can integrate multidimensional pathogeneses. Antispasmodics plus stool consistency modifiers to treat the major symptoms and defecation are the first-line drug treatment. New drugs targeting receptors governing bowel motility, sensation and secretion can be considered, but clinicians must be aware of their potential serious side effects. Psychiatric drugs and modalities may be the final options for treating intractable subjects. Probiotics of multi-species preparations are safe and worth to be considered for the treatment. Antibiotics are promising but their long-term safety and effectiveness are unknown. Diet therapy including exclusion of certain food constituents is an economic measure. Using relatively safe complementary and alternative medicines (CAMs) may be optional to those patients who failed classical treatment. In conclusion, IBS is a heterogeneous disorder with multidimensional pathogeneses. Personalized medicines with multidisciplinary approaches using different classes of drugs, psychiatric measures, probiotics and antibiotics, dietary therapy, and finally CAMs, can be considered.

show abstract

Gender difference on the symptoms, health‐seeking behaviour, social impact and sleep quality in irritable bowel syndrome: a Rome II‐based survey in an apparent healthy adult Chinese population in Taiwan

Cited by 38 publications

References 55 publications

A Survey about Irritable Bowel Syndrome in South Korea

A Survey about Irritable Bowel Syndrome in South Korea

So-Eum Type as an Independent Risk Factor for Irritable Bowel Syndrome: A Population-Based Study in Korea

Irritable bowel syndrome: The evolution of multi-dimensional looking and multidisciplinary treatments

Contact Info

Product

Resources

About