Gender difference on the development of metabolic syndrome: a population-based study in Taiwan

Abstract

Little is known regarding the development of metabolic syndrome. This study examining gender difference in the characteristics of metabolic components aimed to estimate the development of metabolic syndrome in both genders. This nation-wide, population-based survey included 5,880 men and women aged 20-79 years in Taiwan. Metabolic syndrome was defined by the revised National Cholesterol Education Program Adult Treatment Panel III, with adoption of the Asian criteria for abdominal obesity. The results indicate that metabolic syndrome was prevalent in 20.4% of the men and 15.3% of the women. Lipid components occurred the earliest in both genders. The appearance of the first isolated component was earlier in women than in men (mean age 43.4 vs. 45.6 years, P < 0.05). In contrast, the mean prevalent age of metabolic syndrome appeared earlier in men than in women by 4.9 years (mean age 51.3 vs. 56.2 years, P < 0.05). The differences in prevalent age from the appearance of any isolated component to metabolic syndrome were 12.8 years in women and 5.7 years in men, respectively. If men had a body mass index less than 23 kg/m(2) and exercise habits, the difference in the prevalent age from the isolated component to metabolic syndrome was 15.4 years, longer than for all women subjects. We conclude lipid components appeared the earliest. Women had the first isolated component earlier, presenting as metabolic syndrome later than men. The development of metabolic syndrome was slower in subjects without overweight characteristics and with exercise habits.

Type 2 diabetes from pediatric to geriatric age: analysis of gender and obesity among 120 183 patients from the German/Austrian DPV database

“…The proportion of men with T2DM also significantly exceeded that of healthy males in the German population. Adult men usually have more endocrine active visceral fat that favors insulin resistance, a precursor of metabolic syndrome and diabetes (17,18). After the age of 60 years, gender differences in relation to age at diagnosis were no longer present, indicating that risk factors of T2DM were more evenly distributed between men and women ( Fig.…”

Psoriasis Independently Associated With Hyperleptinemia Contributing to Metabolic Syndrome

“…The mean ages at enrollment of cases and controls were 57.39 and 55.63 years, respectively ( 19 in which the prevalences of increased triglyceride levels and reduced HDL cholesterol concentrations were 27.5% and 23.4%, respectively. In the present study, a lower incidence of reduced HDL cholesterol concentrations (10.3%) was seen in patients with psoriasis, but this did not reach statistical significance (P=.24).…”

“…Our results are consistent with those of previous studies. [1][2][3][4][5][6][7][8][9] Metabolic syndrome prevalences of 20% to 40% have been reported among epidemiologic studies 19,20 in Taiwan. Our lower prevalences of metabolic syndrome (16.3% [13 subjects] in controls vs 14.1% [11 patients] in cases) may have occurred because of missing data on lipid profiles and BMI values in our study.…”

Factor analysis of modifiable cardiovascular risk factors and prevalence of metabolic syndrome in adult Taiwanese

“…Although previous reports indicated that MetS prevalence was higher in women in Western countries [26,27], a large health-exam cohort in Taiwan (24,329 subjects) showed greater prevalence among men (15.5%) than women (10.5%) [16]. Results of other studies in Taiwan were contradictory: the prevalence of MetS was lower in women than in men in a population younger than 50 years [28] and 32.55% in men and 19.76% in women in another recent study [29]. We evaluated the percentage of subjects with each established risk factor and MetS prevalence among our subjects based on the AHA/NHLBI definition of MetS (Table 2), but no significant difference between genders was found.…”