Gender difference in ASAS HI among patients with ankylosing spondylitis

Chen, Hsin‐Hua; Chen, Yi Ming; Lai, Kuo-Lung; Hsieh, Tsu‐Yi; Hung, Wei Ting; Lin, Ching Tsai; Tseng, Chih‐Wei; Tang, Kuo‐Tung; Chou, Yin Yi; Wu, Yi; Huang, Chin Yin; Hsieh, Chang‐Wei; Huang, Wen Nan; Chen, Yi Hsing

doi:10.1371/journal.pone.0235678

Cited by 23 publications

(37 citation statements)

References 56 publications

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“…To assist Rheumatologists at TCVGH, in November 2016, we had started assessing the ASDAS, the BASDAI, medications used, and clinical outcomes of all AS patients in our electronic medical record system. Our database's reliability and validity have been examined in our previous publication on the gender difference in ASAS HI among patients with AS ( 15 ). In addition to these disease-specific data, routine demographic data, comorbidities, personal history, and family history are also part of the patient records.…”

Section: Methodsmentioning

confidence: 99%

The BASDAI Cut-Off for Disease Activity Corresponding to the ASDAS Scores in a Taiwanese Cohort of Ankylosing Spondylitis

et al. 2022

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ObjectivesThe Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) has been widely utilized to evaluate disease activity in patients with ankylosing spondylitis (AS) by an arbitrary cut-off of ≥4 to indicate high disease activity and initiate biological therapy. The Ankylosing Spondylitis Disease Activity Score (ASDAS) is a new composite index to assess AS disease activity states that have been defined and validated. ASDAS ≥2.1 was selected as a criterion to start biological therapy. The purpose of this study was to estimate the corresponding BASDAI and ASDAS cut-off in a Taiwanese AS cohort.MethodsFrom November 2016 to October 2018, we assessed the ASDAS and the BASDAI regularly and recorded demographic data for 489 AS patients in Taichung Veterans General hospital (TCVGH) using an electronic patient-reported data system linked to electronic medical records. We used receiver operating characteristic curves with Youden's J statistic to determine the BASDAI values that correspond to ASDAS disease activity cut-offs (i.e., 1.3, 2.1, and 3.5).ResultsIn our population, the best trade-off BASDAI values corresponding to ASDAS -C-reactive protein (CRP) 1.3, 2.1, and 3.5 were 2.1, 3.1, and 3.7, respectively. The optimal BASDAI values corresponding to ASDAS-erythrocyte sedimentation rates 1.3, 2.1, and 3.5 were 2.0, 2.6, and 4.8, respectively.ConclusionWe propose a revised BASDAI cut-off based on our data, as BASDAI scores are commonly used globally. A more reasonable, lower BASDAI cut-off to initiate or change biological therapy will bring us closer to better decisions to treat AS patients.

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Section: Methodsmentioning

confidence: 99%

The BASDAI Cut-Off for Disease Activity Corresponding to the ASDAS Scores in a Taiwanese Cohort of Ankylosing Spondylitis

et al. 2022

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“…The EMRMS database contains information such as AS-related biological characteristics (C-reactive protein [CRP] level and erythrocyte sedimentation rate [ESR]), patient comorbidities, patient history, and family history. The reliability and validity of the data have been veri ed [13].…”

Section: Data Sourcementioning

confidence: 90%

Effect of Electronic Medical Record Management Systems on the Disease Activity and Frequency of Outpatient Visits of Patients with Ankylosing Spondylitis: A cross-sectional

Huang

Liu

Chen

et al. 2022

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BackgroundTo investigate the impact of an electronic medical record management system (EMRMS) on disease activity and the frequency of outpatient visits among patients with ankylosing spondylitis (AS).MethodsWe identified 652 patients with AS who were followed up for at least 1 year before and after the first Ankylosing Spondylitis Disease Activity Score (ASDAS) assessment and compared the number of outpatient visits and average visit time within 1 year before and after the initial ASDAS assessment. Finally, we analyzed 201 patients with AS who had complete data and received ≥3 continuous ASDAS assessments at an interval of 3 months, and we compared the results of the second and third ASDAS assessments with those of the first.ResultsThe number of annual outpatient visits increased after ASDAS assessment (5.8 ± 3.4 vs. 5.4 ± 3.4, p < 0.001), particularly among those with a high initial disease activity. The average visit time was reduced within 1 year after ASDAS assessment (8.7 ± 3.8 vs. 9.2 ± 4.4 min, p = 0.030), especially among patients whose ASDAS-C-reactive protein (CRP) was <1.3 (8.5 ± 3.3 vs. 9.2 ± 4.2 min, p = 0.022). Among patients who received at least three ASDAS assessments, the third ASDAS-CRP was significantly lower than the first (1.5 ± 0.8 vs. 1.6 ± 0.8, p = 0.049).ConclusionThe use of an EMRMS increased the frequency of ambulatory visits among AS patients with high disease activity and reduced the visit time among those with an inactive disease. Continual ASDAS assessments may help control the disease activity of patients with AS.Trial registrationInstitutional Review Board (IRB) of Taichung Veterans General Hospital (TCVGH-IRB No.: CE20145B)

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“…13 A diferencia de lo reportado en otros estudios, en los cuales los hombres presentaron menores valores de ASAS-HI, no encontramos diferencias en cuanto al género tanto en los pacientes con EspAp como con EspAax. 35 En nuestro trabajo, ni la escolaridad ni nivel socioeconómico según escala de Graffar, se asociaron a pobre estado de salud en los grupos evaluados. Sin embargo, el estudio de Min y col., mostró que el estatus económico más alto se asoció de manera independiente a menores valores de ASAS-HI.…”

Section: Tabla 2 Características Demográficas Clínicas Y Tratamiento De Pacientes Con Espaaxunclassified

“…El ASAS HI es una herramienta sencilla para el seguimiento de 27 (24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36) 39 ( 30) los pacientes en la atención diaria. Su uso puede ser un gran aporte a la evaluación de pacientes con EspA con un enfoque más general de la atención médica.…”

Section: Tabla 2 Características Demográficas Clínicas Y Tratamiento De Pacientes Con Espaaxunclassified

ASAS Health Index performance in real-life Spondyloarthritis patients

Martire

Bosch

Airoldi

et al. 2021

Rev. Argent. Reumatol.

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Introduction: the “Assessment of Spondyloarthritis International Society Health Index” (ASASHI) questionnaire was developed to globally measure function and health status in patients with spondyloarthritis (SpA). Cut-off points have been proposed to determine different health states that were poorly evaluated in real-life patients. Objectives: to describe the health status measured by ASAS-HI in Argentine patients with axial SpA (AxSpA) and peripheral SpA (SpAp) in daily practice and to evaluate the factors associated with poor health. Materials and methods: cross-sectional, analytical and multicenter study. Patients with SpAax and SpAp were consecutively included according to ASAS criteria, from 15 Argentine centers. Statistical analysis: descriptive statistics, bivariate and multivariate analysis (multiple logistic regression) were performed to evaluate the factors associated with poor health status (ASAS-HI≥12). To analyze the construct validity of the tool, Spearman correlation was performed between the ASAS-HI and other disease evaluation parameters. Results: 274 patients with SpA were included, with a mean age of 49 (± 14) years and a median duration of the disease of 62 months (p25-75: 24-135), 155 (56.6%) were male, 129 patients (47%) with AxSpA and 145 (52.9%) SpAp. According to the ASAS-HI, 119 patients (43.4%) had good health, 117 (42.7%) had moderate health and 38 (13.9%) had poor health. In patients with SpAp, the mean ASAS-HI value was 7 (p25-75: 3-10). The ASAS-HI positively correlated with: DAS28: rho: 0.5 (p <0.001) and HAQ: rho: 0.54 (p <0.001). The variable independently associated with poor health status was DAS28 (OR: 1.9, 95% CI 1.1-3.4, p: 0.029). In patients with AxSpA, the mean ASAS-HI value was 6 (p25-75: 2.75-10). The ASAS-HI showed correlation with: BASDAI: rho: 0.7 (p <0.001), ASDAS-ERS: rho: 0.7 (p <0.001), ASQoL: rho: 0.8 (p<0.001), BASFI rho: 0.75 (p <0.001) 0.001). The variable that was independently associated with poor health was the ASDAS-ERS (OR 6.6, 95% CI 2-22, p 0.002). Conclusion: poor health status was independently associated with higher disease activity in patients with AxSpA and SpAp. The ASAS-HI correlated with other parameters of the disease, which reinforces the construct validity of this new tool.

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Gender difference in ASAS HI among patients with ankylosing spondylitis

Abstract: Objective To assess the associations of the

Cited by 23 publications

References 56 publications

The BASDAI Cut-Off for Disease Activity Corresponding to the ASDAS Scores in a Taiwanese Cohort of Ankylosing Spondylitis

The BASDAI Cut-Off for Disease Activity Corresponding to the ASDAS Scores in a Taiwanese Cohort of Ankylosing Spondylitis

Effect of Electronic Medical Record Management Systems on the Disease Activity and Frequency of Outpatient Visits of Patients with Ankylosing Spondylitis: A cross-sectional

ASAS Health Index performance in real-life Spondyloarthritis patients

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