Abstract: Aims: This study examined medication use for attention-deficit/hyperactivity disorder (ADHD) among children and adolescents by gender in Finland during 2008–2018. Methods: Aggregated data on medication use for ADHD from 2008 to 2018 were extracted from the nationwide register on reimbursed prescriptions. The annual prevalence of ADHD medication use was calculated as the number of children (6–12 years) and adolescents (13–17 years) per calendar year with at least one ADHD medication purchase divided by… Show more
“…The use of child and adolescent psychiatric (CAP) services has increased worldwide [1][2][3][4][5][6] and this has led to the expansion of open care services [7,8]. These include parent training [9,10], cognitive-behavioral therapy [11,12], school-based contingency management [13] and pharmacotherapy [14][15][16][17]. There are also a growing number of services for those who need more intensive open care treatment, due to the severity of their condition [2,18], and these include specific multisystemic treatment models [19].…”
Inpatient treatment is an important part of child and adolescent psychiatric (CAP) care. This nationwide study explores the changes in length of stay, recurrent hospitalization, functioning level, suicidality, violence and diagnoses of CAP inpatients in Finland in 2000, 2011 and 2018. We obtained comprehensive questionnaire data on each study year from 93 to 95% of all CAP wards in Finland. We split the 1276 inpatients into two age groups in each study year: under 13 and 13–18. The median length of stay in inpatient treatment decreased from 82.0 days in 2000 to 20.5 days in 2018 (p < 0.001) and recurrent hospitalization increased from 38 to 46%. General functioning, which was evaluated by the Children’s Global Assessment Scale, deteriorated by an average of six points between 2000 and 2018. Violent threats decreased from 21.5 to 16.6% and violent acts decreased from 26.9 to 20.3%. Suicidal threats decreased from 42.6 to 23.3% in those aged under 13 and remained stable among those aged 13–18. In the 13–18 group, there was an increase in the diagnoses of ADHD, from 5.0 to 16.9% and depression, from 25.1 to 41.7%. However, psychosis decreased from 23.2 to 12.6% in the older age group. In the whole cohort, anxiety disorders increased from 7.6 to 15.6%. The overall picture does not show that CAP inpatients have become more disturbed. While the general functioning of CAP inpatients deteriorated somewhat over the 2000–2018 study period, symptoms of suicidality and violence remained stable or decreased. There was also a continuous increase in short-term treatment.
“…The use of child and adolescent psychiatric (CAP) services has increased worldwide [1][2][3][4][5][6] and this has led to the expansion of open care services [7,8]. These include parent training [9,10], cognitive-behavioral therapy [11,12], school-based contingency management [13] and pharmacotherapy [14][15][16][17]. There are also a growing number of services for those who need more intensive open care treatment, due to the severity of their condition [2,18], and these include specific multisystemic treatment models [19].…”
Inpatient treatment is an important part of child and adolescent psychiatric (CAP) care. This nationwide study explores the changes in length of stay, recurrent hospitalization, functioning level, suicidality, violence and diagnoses of CAP inpatients in Finland in 2000, 2011 and 2018. We obtained comprehensive questionnaire data on each study year from 93 to 95% of all CAP wards in Finland. We split the 1276 inpatients into two age groups in each study year: under 13 and 13–18. The median length of stay in inpatient treatment decreased from 82.0 days in 2000 to 20.5 days in 2018 (p < 0.001) and recurrent hospitalization increased from 38 to 46%. General functioning, which was evaluated by the Children’s Global Assessment Scale, deteriorated by an average of six points between 2000 and 2018. Violent threats decreased from 21.5 to 16.6% and violent acts decreased from 26.9 to 20.3%. Suicidal threats decreased from 42.6 to 23.3% in those aged under 13 and remained stable among those aged 13–18. In the 13–18 group, there was an increase in the diagnoses of ADHD, from 5.0 to 16.9% and depression, from 25.1 to 41.7%. However, psychosis decreased from 23.2 to 12.6% in the older age group. In the whole cohort, anxiety disorders increased from 7.6 to 15.6%. The overall picture does not show that CAP inpatients have become more disturbed. While the general functioning of CAP inpatients deteriorated somewhat over the 2000–2018 study period, symptoms of suicidality and violence remained stable or decreased. There was also a continuous increase in short-term treatment.
“…6,24 For example, prevalence rates of ADHD medication use among the child population in Finland have been relatively low, particularly among girls, 24,25 but the rates of ADHD diagnoses and medication use are increasing relatively rapidly. 26 Sex differences are also important to consider because the rates of ADHD vary by sex in middle childhood. Emotion dysregulation and externalizing behaviors drive referral for ADHD.…”
mentioning
confidence: 99%
“…Altogether, with our study, we add to the global understanding of the RAE in ADHD by providing a more-complete picture of the phenomenon from a single jurisdiction where the rates of children with ADHD have increased somewhat rapidly and delayed school entry has decreased. 13,26 First, we hypothesized that with delayed school entry being somewhat rare in Finland, there would be at least a modest RAE in prescribing ADHD medication for children. Second, given that difference in maturity is more extreme at young ages, we expected that the RAE in ADHD medication use would be stronger at ages 6 to 7, when children start primary education.…”
OBJECTIVES: The youngest children in a classroom are at increased risk of being medicated for attention-deficit/hyperactivity disorder (ADHD). We examined the association between children's birth month and ADHD medication rates in Finland. METHODS: Using a population-based study, we analyzed ADHD medication use among children born in 2005 to 2007. Cases (n = 7054) were identified from the first purchase of medication for ADHD. Cox proportional hazard models and hazard ratios (HRs) were examined by birth month and sex. Finnish children start first grade in the year of their seventh birthday. The cutoff date is December 31. RESULTS: Risk of ADHD medication use increased throughout the year by birth month (ie, January through April to May through August to September through December). Among boys born in September to December, the association remained stable across cohorts (HR: 1.3; 95% confidence interval [CI]: 1.1-1.5). Among girls born in September to December, the HR in the 2005 cohort was 1.4 (95% CI: 1.1-1.8), whereas in the 2007 cohort it was 1.7 (95% CI: 1.3-2.2). In a restricted follow-up, which ended at the end of the year of the children's eighth birthday, the HRs for boys and girls born in September to December 2007 were 1.5 (95% CI: 1.3-1.7) and 2.0 (95% CI: 1.5-2.8), respectively. CONCLUSIONS: Relative immaturity increases the likelihood of ADHD medication use in Finland. The association was more pronounced during the first school years. Increased awareness of this association is needed among clinicians and teachers. WHAT'S KNOWN IN THIS SUBJECT: The relative age effect (RAE) in attention-deficit/hyperactivity disorder (ADHD) indicates that ADHD medication use is more common in the relatively youngest children within a school grade. Within-country sex differences in ADHD medication use vary and are among the largest in Finland. WHAT THIS STUDY ADDS: This population-based study reveals that the RAE in ADHD medication use among children was more pronounced during the first school years (ages 6-8). The RAE in ADHD medication was stable among boys across 3 cohorts but increasing among girls.
“…With respect to ADHD diagnosis, as patient gender moderates symptom manifestations, boys are more likely to receive an ADHD diagnosis even when not all the criteria have been met (false-positive diagnostic error), while girls are less likely to receive a diagnosis of ADHD even when they fulfill the criteria (false-negative diagnostic error). Therefore, considering the heuristics effect in the diagnostic process is another possible explanation for the differences we observe between clinical and epidemiological data in ADHD [13,24].…”
Section: Adhd Overdiagnosis and Issue Of Gender Biasmentioning
confidence: 80%
“…A large body of ADHD research shows that children born close to kindergarten or school cut-off dates, and who are therefore up to a year younger than their classmates, are 30 to 60% more likely to be diagnosed with ADHD [11][12][13][14]. In this regard, there is evidence that a child's birthdate influences considerably the subjective evaluations of teachers in identifying whether that child is exhibiting ADHD symptoms.…”
Section: Adhd Overdiagnosis and Issue Of Age Biasmentioning
Background
Regarding the controversy about the overdiagnosis of Attention Deficit/Hyperactivity Disorder (ADHD) in children and adolescents there are two main directions addressed as issue of age bias and issue of gender bias. In this relation, replication of findings demonstrating significant overdiagnosis is of importance which make the systematic evaluation of such occurrence necessary.
Objective
The seminal study by Bruchmüller, Margraf & Schneider, 2012 is replicated here, although in a different cultural context, in this case Iran, as ADHS might be perceived differently there. We assessed both gender bias and the impact of potential overdiagnosis on treatment recommendations.
Methods
A total of 344 licensed Iranian psychiatrists (mean age = 45.17, SD = 9.50) participated in this study. Each psychiatrist received a cover letter that introduced the study as well as a case vignette. Overall, there are eight different cases, one child with ADHD and three non-ADHD children, for both a boy (Ali) and a girl (Sara). Participants also received a questionnaire requesting their particular diagnosis, treatment recommendation and the therapist’s sociodemographic information. Chi square tests and multiple logistic regression were applied for data analyses.
Results
Overdiagnosis occurred in both girl and boy children, although overdiagnosis was 2.45 more likely in boys than in girls (p < 0.01). With respect to the psychiatrist’s gender, we detected no difference between males or females, as both overdiagnosed ADHD in boys (pfemale < 0.01 and pmale < 0.01). Furthermore, ADHD overdiagnosis had a direct impact on medication prescription (p < 0.01).
Conclusion
This study suggests that diagnosticians should strictly adhere to diagnostic criteria to minimize diagnostic error.
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