“…Gemini surfactants, which differ from traditional monomeric surfactants that have only one lipophilic tail and one lipophobic head group, are a novel series of surfactants that have two lipophilic chains and two lipophobic head groups chemically bonded together by the spacer. − In comparison with the corresponding traditional monomeric surfactant, a gemini surfactant possesses remarkable physicochemical properties, including lower Krafft point, excellent solubility, lower critical micelle concentration (cmc), − higher surface activities, better wetting, foaming, and lime-soap dispersing properties, higher thermal stability, and biological properties. , Due to the characteristic structure and outstanding activities, gemini surfactant has been extensively used for multiple applications such as conventional detergent, cosmetic, food industry, facile soft template, nonviral gene delivery vector, drug delivery agent, or antimicrobial. ,− …”