Gemase for treatment of intraretinal hemorrhages and hemophthalmia at thrombocytopenia due to acute myeloid leukemia in children

Abstract

Intraretinal hemorrhages are the most common eye lesion in patients with hemoblastosis. Such patients have lower hemoglobin and platelet counts than those who haven’t hemorrhages. Hemophthalmia is the penetration of blood into the vitreous body or into one of the spaces formed around it. The reason for this may be vessels damage of the retina or newly formed vessels of the retina, that are more fragile compared to normal. Thrombocytopenia is one of the most common hematological symptoms in different blood diseases. Thrombocytopenia is a significant decrease in the number of circulating platelets (less than 100 × 109 /l), which leads to bleeding. Ophthalmic problems can occur in acute leukemia with thrombocytopenia, which can affect any anatomical structures of the eye. The relationship between hematological parameters and the nature of changes in the fundus has been established. The article provides analysis of two clinical cases of hemophthalmia in pediatric patients with acute myeloid leukemia and description of positive dynamics on therapy with Gemase. Parents gave their consent to use information about the child, including fotos, in the article.