2003
DOI: 10.1007/s00106-002-0770-1
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Gegenw�rtige Theorien zur Cholesteatomentstehung

Abstract: Zur Entstehung der Cholesteatome gibt es eine Reihe unterschiedlicher Theorien, die z.T. sehr kontrovers diskutiert werden.Während das kongenitale Cholesteatom selten zu sein scheint, liefern neuere Untersuchungen zur Entstehung des erworbenen Cholesteatoms Hinweise für eine Kombination der Retraktionstaschentheorie und der Theorie der Hyperplasie der Basalzellschicht als wahrscheinlichen Erklärungsan-satz. Dies wird aus der Epidemiologie und Untersuchungen zum biologischen Verhalten der Matrix und Perimatrix … Show more

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Cited by 11 publications
(3 citation statements)
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“…Depending on the character of lesions to the middle ear mucous, different types of this abnormality are distinguished: simple chronic otitis media, chronic cholesteatoma otitis media, chronic granulomatous otitis media, and chronic otitis media associated with specific diseases. Particularly notable is the occurrence of cholesteatoma and granulation tissue, which are characterized by a tendency to damage the bone tissue, implying the risk of otogenic intracranial and intratemporal complications ( Figure 1 ) [ 1 – 3 ].…”
Section: Introductionmentioning
confidence: 99%
“…Depending on the character of lesions to the middle ear mucous, different types of this abnormality are distinguished: simple chronic otitis media, chronic cholesteatoma otitis media, chronic granulomatous otitis media, and chronic otitis media associated with specific diseases. Particularly notable is the occurrence of cholesteatoma and granulation tissue, which are characterized by a tendency to damage the bone tissue, implying the risk of otogenic intracranial and intratemporal complications ( Figure 1 ) [ 1 – 3 ].…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, facial paralysis might be caused by erosion of the facial canal and disturbances of the equilibrium organ due to detraction of the semicircular fistulas. Fortified inflammation causes mastoiditis, meningitis, intracranial abscesses, and sinus vein thrombosis [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ].…”
Section: Introductionmentioning
confidence: 99%
“…Cholesteatoma requires a complete resection to avoid recurrence. Especially, the proliferation of this epithelium in the middle ear cavity and further growth into the mastoid and lateral skull base can lead to life-threatening complications [7]. Thus, the goal during surgery is a complete removal while recovering or preserv-ing the hearing ability.…”
Section: Introductionmentioning
confidence: 99%