“…A surprising finding was that among all the factors tested, only HGF significantly accelerated the wound closure in human AEC monolayers. Other factors, such as bFGF, BMP-5, FGF-4, KGF, FGF-10, GDF-15, IGF-1, OPG, and VEGF, which are known to be associated with cell proliferation, wound closure, and/or inflammation in the cells from the different organs, had no apparent effect on wound closure (1,19,22,25,27,29,42,51). These soluble factors are likely important in other organs or species, which could have different levels of receptors and receptor activation.…”