Abstract:BACKGROUND/OBJECTIVES
Treatment of children with CNS NGGCT remains challenge: 5y OS is 60 – 80%; relapses are very aggressive.
DESIGN/METHODS
Between 2003 and 2019, 14 children (median age 10.5, range 4 – 16 years) with localized intracranial NGGCT were treated with RT after induction chemotherapy (focal – 4, WVI+boost – 6, WBI+boost – 3, CSI+boost – 1). Tumor markers were elevated in 13 patients: 6 – AFP, 5 – HCG, 2 – both. … Show more
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