GC-MS Determination of Bioactive Constituents of the Methanolic Fractions of Cnidoscolus aconitifolius

Achi, Ngozi; Ohaeri, O. C.

doi:10.9734/bjpr/2015/13893

Cited by 17 publications

(13 citation statements)

References 13 publications

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“…Also, hepta-9, 10, 11-trienoic acid and octadecenoic acid has antitumor and antiviral property respectively. The result of this study is in concurrence with the research of Achi and Ohaeri (2015) on GC-MS determination of bioactive constituents of the The result of this analysis revealed that the plant contained promising novel class of pharmaceutical active compounds that might play beneficial roles in the treatment of diverse detailed study. Further investigation into the pharmacological importance of S. uliginosa (Sw) and their diversity and detailed phytochemistry may add new knowledge to the information in the traditional medicinal systems.…”

Section: Resultssupporting

confidence: 81%

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GC/MS Determination of Bioactive Constituents of Methanol Fraction of Spilanthes uliginosa (Sw) Leaves

Uraku¹

2016

Research J. of Medicinal Plant

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Plant as a source of herbal medicine is the oldest form of medicine known to mankind. It was the mainstay of many earlier civilization and still the most widely practiced form of medicine in the world currently. The GS-MS analysis of the leaf extract of Spilanthes uliginosa (Sw) was investigated. The analysis revealed the presence of six peaks from the chromatogram which showed six phytocompounds. The major phytocompounds identified in the leaf extract are hexadecanoic acid (8.68%), hepta-9, 10, 11-trienoic acid (19.36%), octadecenoic acid (8.14%), 5-hydroxylmethyl heptadecane (14.02%), docosane aldehyde (41.72%) and 1-ethoxyoctadecane (8.08%). The presence of these assorted chemicals may be responsible for the beneficial potentials of Spilanthes uliginosa (Sw) in tradomedicine.

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Section: Resultssupporting

confidence: 81%

“…The identification of these bioactive constituents of plants is crucial in unviering some essential compounds of economic values for production of multifarious chemical substances and also for finding their therapeutic agents (Achi and Ohaeri, 2015).…”

Section: Introductionmentioning

confidence: 99%

GC/MS Determination of Bioactive Constituents of Methanol Fraction of Spilanthes uliginosa (Sw) Leaves

Uraku¹

2016

Research J. of Medicinal Plant

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“…Nearly 35 compounds were identified and among those compounds the studies showed that the presence of the derivative of dodecanoic acid namely dodecanoic acid, methyl ester and dodecanoic acid, 1,2,3-propanetriyl ester in acetone extract and this may be responsible for antibacterial activity 9 . In Cnidoscolus aconitifolius, the phyto-compound dodecanoic acid, 1,2,3-propanetriyl ester showed antiarthritic, nematocide, and hepatoprotective activities 10 . The methanolic extract of Ipomoea pescaprae was identified by GC-MS analysis.…”

Section: Fig 5: Mass Spectrum and Chemical Structure Of Hexadecanoicmentioning

confidence: 99%

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2020

IJPSR

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Phymatosorus scolopendria (Burm. F.) Pic. Serm. belongs to the family Polypodiaceae which is commonly known as musk-fern or wartfern. Medicinally, the experimental plant possesses insect repellent, antiinflammatory and bronchodilator activity and hence used ethnomedicinally by tribal people, but was not explored for its bioactive compounds. Hence, the objective of this study was to determine the bioactive compounds present in the methanolic extract of Phymatosorus scolopendria by Gas Chromatography-Mass Spectrum. The methanolic extract of the experimental plant revealed the presence of four phytoconstituents, namely dodecanoic acid, 1,2,3-propanetriyl ester, myristic acid vinyl ester, 4nitrophenyl laurate and hexadecanoic acid, 4-nitrophenyl ester with peak values 8.98, 53.29, 26.91 & 10.82. The predicted biological activities for the present compounds identified when referred in the literature shows antioxidant, antibacterial, antiviral, candidicidal, hypocholestrolemic, antiarthritic, hepatoprotective, mosquito repellent, antimicrobial, anticancer and cosmetics. The compounds were identified by comparing their retention time and peak area with that of literature and interpretation of mass spectra. The research could be continued to find out the therapeutic importance of all the compounds in future.

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“…Due to increased demand of natural products from medicinal plants in healthcare serves worldwide, herbal plant producers have commenced the use of the most apt extraction methods in order to see and detach the chemical compounds present in them (Achi and Ohaeri, 2015). The main intent of detection of phytocompound in plants is to arrive at the therapeutically desired active portion/fraction and to purge superfluous materials (Waldesch et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

“…The main intent of detection of phytocompound in plants is to arrive at the therapeutically desired active portion/fraction and to purge superfluous materials (Waldesch et al, 2003). An exceptional facet of advanced plants is their competence to manufacture various organic chemicals of high structural density (Achi and Ohaeri, 2015). The awareness of the chemical constituents of plants is not only advantageous for discovery of curative agents but also for disclosing new sources of important economic phytocompounds for the synthesis of complex chemical substances and for discovering the actual significance of folklorica (Uraku et al, 2015b).…”

Section: Introductionmentioning

confidence: 99%

Determination of Chemical Compositions of Cymbopogon citratus Leaves by Gas Chromatography-Mass Spectrometry (GC-MS) Method

Uraku¹

2015

Research J. of Phytochemistry

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Cymbopogon citratus, commonly known as lemongrass, is a tropical perennial herb belonging to the family Poaceae (true grasses). According to tradomedicine practitioners, this plant is claimed to have therapeutic potentials in numerous diseases. This study is aimed at determining the possible bioactive components of leaves of the C. citratus using Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Six compounds were identified in the methanol leaf extract and they include; hexadecanoic acid (8.11%), hepta-9,10,11-trienoic acid (17.43%), octadecenoic acid (8.41%), 2-ethenyltetradecan-1-ol (13.28%), eicosane aldehyde (37.56%) and 1-ethoxyoctadecane (15.20%) as the major chemical constituents. The presence of these compounds in the plant extract may at least be responsible for the pharmacological properties of Cymbopogon citratus and thus recommended as plant of phytopharmaceutical importance.

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GC-MS Determination of Bioactive Constituents of the Methanolic Fractions of Cnidoscolus aconitifolius

Cited by 17 publications

References 13 publications

GC/MS Determination of Bioactive Constituents of Methanol Fraction of Spilanthes uliginosa (Sw) Leaves

GC/MS Determination of Bioactive Constituents of Methanol Fraction of Spilanthes uliginosa (Sw) Leaves

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Determination of Chemical Compositions of Cymbopogon citratus Leaves by Gas Chromatography-Mass Spectrometry (GC-MS) Method

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