GB virus C/hepatitis G virus infection among Korean patients with liver diseases and general population

Park, Young-Min; Mizokami, Masashi; Nakano, Tatsunori; Choi, Jong-Young; Chen, Kun; Byun, Byung-Hun; Cho, Chang-Hoon; Youngtae, Jung; Paik, Soon-Young; Yoon, Shin Hee; Mukaide, Motokazu; Kim, Boo-Sung

doi:10.1016/s0168-1702(97)01450-0

Cited by 15 publications

(7 citation statements)

References 16 publications

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“…Multiple studies of HPgV-1 prevalence in hepatitis/liver disease patients have been reported, including in China, India, Indonesia, Iran, Japan, Lebanon, Mongolia, Myanmar, Nepal, Pakistan, Qatar, Saudi Arabia, Singapore, South Korea, Taiwan, Thailand, Turkey, the United Arab Emirates and Vietnam. [77][78][79][80][81][82][84][85][86][87][88][89][90][91][92][93][94][95][96][97][98][99]101,107,112, HPgV-1 prevalence rates above 10% were observed in China, 90,98,99,107,118,119,124,135,[142][143][144] India, 80,85,92,117,126 Indonesia, 93 Iran, 123 Japan, 66,125,131,[138][139]…”

Section: Prevalence In Hepatitis and Liver Disease Patientsmentioning

confidence: 99%

Human pegivirus type 1 infection in Asia—A review of the literature

Zimmerman

Blackard

2021

Reviews in Medical Virology

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The human pegivirus type 1 (HPgV-1)-as known as hepatitis G virus and GB virus C-is a common single-stranded RNA flavivirus. Because few studies have demonstrated an association between HPgV-1 infection and disease, screening for HPgV-1 is not performed routinely. Nonetheless, a beneficial impact of HPgV-1 infection on HIV disease progression has been reported in multiple studies. Given the burden of HIV in Asia and the complex interactions between viral co-infections and the host, we provide a comprehensive overview of the existing data from Asia on HPgV-1 infection, including the prevalence and circulating genotypes in all Asian countries with data reported. This review highlights the research conducted thus far and emphasizes the need for additional studies on HPgV-1 across the Asian continent.

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Section: Prevalence In Hepatitis and Liver Disease Patientsmentioning

confidence: 99%

Human pegivirus type 1 infection in Asia—A review of the literature

Zimmerman

Blackard

2021

Reviews in Medical Virology

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“…The similarities observed between HGBV-C/ HGV and HCV suggest that different strains of HGBV-C/HGV, probably related to different geographical location, may exist, as occurred with HCV [5]. Thus, several authors have described the existence of at least three different genotypes of HGBV-C/HGV [6][7][8][9][10]. Muerhoff et al [6,7] studying the 5)-UTR showed the prevalence of these HGBV-C/HGV genotypes with geographical distribution: genotype 1 in West Africa, 2a and 2b in Europe and USA and genotype 3 in Asia.…”

Section: Introductionmentioning

confidence: 99%

Phylogenetic Analysis of Hepatitis GB Virus Type C/Hepatitis G Virus in Spanish Patients with Chronic Hepatitis B or C Virus Infection

López‐Alcorocho

Amaro²,

Cabrerizo³

et al. 1998

Intervirology

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The nucleotide sequence of hepatitis GB virus type C (HGBV-C)/hepatitis G virus (HGV) NS3/helicase and 5′-untranslated regions from 23 Spanish patients were analyzed to assign the HGV isolates one of the proposed HGBV-C/HGV genotypes. The analysis of the evolutionary distance frequency showed that the distances among all sequences in NS3/helicase region were distributed around a single peak of 0.20, suggesting that all included sequences belonged to the same HGBV-C/HGV genotype. By contrast, in the 5′-untranslated region, all the distances corresponding to our sequences and those of the HGBV-C/HGV types 2 and 3 were distributed around a major peak of 0.03. The remaining distances corresponding to the HGBV-C/HGV type 1 sequences were distributed around a minor peak of 0.11. The phylogenetic tree and pairwise comparison of evolutionary distances among the 5′-untranslated region of the infected patients and each HGBV-C/HGV genotype demonstrated that our HGBV-C/HGV isolates belonged to subtype 2a (17/23; 78%) and 2b (5/23; 22%). No relation was found between HGBV-C/HGV subtype and hepatitis B or C virus infection.

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“…The most common type of GBV‐C in Japanese patients studied was the Asian type and its prevalence was 88% in the GBV‐C‐positive patients. Asian type was the major sequence of GBV‐C reported in studies from Beijing, 30 Korea 31 and Mongolia, 26 indicating that this virus was transmitted through a common root.…”

Section: Discussionmentioning

confidence: 92%