Gated Cardiac Scanning

Wh, Berninger; Rw, Redington; Doherty, Patricio Santillán; Mj, Lipton; Carlsson, Erik

doi:10.1097/00004728-197904000-00002

Cited by 41 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, calculation of slice ejection fraction from-area time curves yields values that are less than the true value because of an overestimation of endsystolic and an underestimation of end-diastolic dimensions. 6 The reformatted images in the coronal and sagittal planes, although not adding any new information not available in the individual slices, did provide images in the right anterior oblique and left anterior oblique views, which can be useful when comparing the results with studies performed with other methods such as contrast or isotope angiography.…”

mentioning

confidence: 99%

Detection and quantitation of myocardial infarction in vivo using transmission computed tomography.

Doherty¹,

Lipton²,

Berninger³

et al. 1981

Circulation

View full text Add to dashboard Cite

SUMMARY In vivo studies were performed on 28 dogs to evaluate the usefulness of transmission computed tomography (CT) in the detection and quantitation of experimentally induced myocardial infarction. Intravenously administered contrast material was required to define the internal structure of the heart and to differentiate normal from infarcted tissue. Transmural IN VIVO computed transmission tomography (CT) adds to noninvasive cardiac imaging the capacity for high spatial resolution imaging. CT studies of myocardial infarction in vitro1-4 suggested the value of this technique in the detection and quantitation of myocardial infarcts. It was believed that with the scan times available, cardiac motion would prevent practical application.5 In this feasibility study, performed using experimentally induced myocardial infarctions in dogs, the capability of a whole-body scanner, which has a scan time of 4.8 seconds, to provide useful images was assessed. The studies were aimed at answering the following questions:(I) How early after coronary arterial ligation can infarcts be identified in vivo?(2) Must the scans be performed with contrast enhancement, and if so, is it better to deliver the contrast agent by infusion or by bolus? Materials and Methods InstrumentationThese studies were performed using a whole-body scanner (General Electric CT/T 7800) with software and hardware modifications designed to permit rapid sequence scanning and retrospective ECG gating. The data for the gated reconstructions were obtained retrospectively by selecting appropriate views from a series of scans taken with a simultaneous continuous recording of the ECG as previously described.6 lhe gating window was typically about 100 msec, arid by using a time overlapping sequence, up to 24 gated mniages per cardiac cycle could be displayed in a nonflicker cine mode similar to those obtained with gated isotope studies. Special display software permitted reformatting of the display data from a series of cojitiguous axial slices into any plane (coronal, sagittal or oblique). Image data were scaled in accord with the old Hounsfield (+ 500) scale, in which 5 units correspond to approximately 1% of the attenuation coefficient of water. Imaging and Contrast EnhancementBefore imaging, the fasting dogs were anesthetized with sodium pentobarbital (30 mg/kg), paralyzed with succinylcholine (2 mg/kg), intubated, and ventilated with a Harvard dual-phase respirator using humidified room air. The dogs were held supine in a Plexiglas cradle and placed head first in the scanner. The level of the cardiac apex was found by palpation and marked on the chest. This reference mark was used with the instrument's alignment lights to position the dog in the scanner. A series of scans was obtained without contrast medium from the apex to tne base of the heart at 1-cm intervals to confirm the position of the heart and to act as control scans. Respiration was suspended at full inspiration throughout the duration 597 by guest on

show abstract

mentioning

confidence: 99%

Detection and quantitation of myocardial infarction in vivo using transmission computed tomography.

Doherty¹,

Lipton²,

Berninger³

et al. 1981

Circulation

View full text Add to dashboard Cite

show abstract

“…There was agreement on the site of the Computed tomography of left ventnrcular aneurysms aneurysm in all cases. In view of the small numbers studied it is not possible to comment critically on the distribution of the different sites of the aneurysms, but as might be expected anterior and apical aneurysms (19) were much commoner than posterior ones (1).…”

Section: Resultsmentioning

confidence: 99%

Computed tomographic assessment of left ventricular aneurysms.

Foster¹,

Sekiya²,

Brownlee³

et al. 1984

Heart

View full text Add to dashboard Cite

“…61 The principles of CT scanning were originally invented by the British engineer Godfrey Hounsfield (1919Hounsfield ( -2004, who was awarded the 1979 Nobel Prize in medicine and physiology, and the first CT scan was announced in 1972. 62 As the characteristics of the internal structure of heart and vessels are readily attainable from CT images, and the recently available scanners are capable of obtaining hundreds of "slices" per rotation, 63 this technique is now widely used in coronary disease work-up. 64…”

Section: History Of X-ray Examination Of the Heartmentioning

confidence: 99%

Of MIs and Men—A Historical Perspective on the Diagnostics of Acute Myocardial Infarction

Cervellin

Lippi

2014

Semin Thromb Hemost

View full text Add to dashboard Cite

The history of myocardial infarction (MI) diagnostics has gone through a continuous evolution over the past century, when several new discoveries have contributed to remarkably increase the number of patients appropriately diagnosed with this condition. The tale "of MIs and Men" displays rather a long history, since atherosclerosis was found to be present in humans several centuries before modern civilization and the identification of the most prevalent risk factors. It was only at the end of the 19th century and at the beginning of the 20th century that the physicians acknowledged that MI is principally sustained by coronary thrombosis, and that the clinical picture of MI could be subsequently confirmed at autopsy. With the first description of the electrocardiogram (ECG) in the 1910s and 1920s, the history of modern MI diagnostics really began. Additional important discoveries followed, which are mainly represented by radiography, echocardiography, computed tomography, and magnetic resonance imaging of the heart. Another major breakthrough occurred at the down of the third millennium, with the development of commercial immunoassays for the measurement of cardiac troponin I and T, which represent now the cornerstones for identifying any kind of myocardial injury, thus including MI. The major advancements in the understanding of MI pathophysiology and the progressive introduction of efficient diagnostic tools will be described and discussed in this narrative historical review.

show abstract

Gated Cardiac Scanning

Cited by 41 publications

References 0 publications

Detection and quantitation of myocardial infarction in vivo using transmission computed tomography.

Detection and quantitation of myocardial infarction in vivo using transmission computed tomography.

Computed tomographic assessment of left ventricular aneurysms.

Of MIs and Men—A Historical Perspective on the Diagnostics of Acute Myocardial Infarction

Contact Info

Product

Resources

About