GATA3 Expression in Prostatic Adenosquamous Carcinoma: A Potential Diagnostic Pitfall
Susan K. Potterveld,
Sean R. Williamson,
Khaleel I. Al-Obaidy
et al.
Abstract:Urothelial carcinoma and prostatic adenocarcinoma can have overlapping histologic features and in some instances pose challenges to pathologists. GATA binding protein 3 (GATA3) immunohistochemistry (IHC) is a well-established tool to aid in this specific diagnostic dilemma as it has been shown to be a sensitive marker for urothelial carcinoma and a putatively specific marker in excluding prostatic adenocarcinoma. However, in encountering an index tumor of prostatic adenosquamous carcinoma positive for GATA3, h… Show more
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