GATA-3 expression and its correlation with prognostic factors and survival in canine mammary tumors
Gabriel Saraiva Diniz-Gonçalves,
Anna Hielm-Björkman,
Vanessa Bonfim da Silva
et al.
Abstract:IntroductionThe transcription factor GATA-3 plays a significant role in mammary gland development and differentiation. Recent studies on human oncology have demonstrated its association with favorable pathologic factors in breast cancer. Canine mammary tumours, proposed as comparative and translational study models, have epidemiological, clinical, biological, and genetic characteristics similar to those of human breast cancers.MethodsHere, we evaluated the frequency of GATA-3 expression in mammary tumors of do… Show more
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