Gastroscopic Observations in Rosacea

Usher, B.

doi:10.1001/archderm.1941.01500020106011

Cited by 13 publications

(3 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…duodenal ulcer, gastrie carciuoma. It would have been interesting to have been able to demonstrate a link between acne rosacea and the blood groups, rosacea sometimes being associated with gastritis (Usher, 1941). This, however, it was not possible to do.…”

Section: Resultsmentioning

confidence: 99%

Abo Blood Groups and Skin Diseases.

Macsween

Syme

1965

Br J Dermatol

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Abo Blood Groups and Skin Diseases.

Macsween

Syme

1965

Br J Dermatol

View full text Add to dashboard Cite

“…Numerous associations have been reported between digestive tract disorders and rosacea. Such diseases include ulcerative colitis, 1 Crohn's disease, 2 gastritis, 3 coeliac disease, 4 hypochlorhydria, 5 abnormalities in jejunal mucosa 4 and Helicobacter pylori infection 6 …”

Section: Reportmentioning

confidence: 99%

Remission of rosacea induced by reduction of gut transit time

Kendall¹

2004

Clin Exp Dermatol

View full text Add to dashboard Cite

Rosacea is a chronic disorder characterized by hypersensitivity of the facial vasculature, presenting with intense flushing eventually leading to chronic erythema and telangiectasia. Although the precise aetiology of rosacea is not known, numerous associations with inflammatory gastrointestinal tract disorders have been reported. Furthermore, substance P-immunoreactive neurones occur in considerably greater numbers in tissue surrounding affected blood vessels suggesting involvement of neurogenic inflammation and moreover plasma kallikrein-kinin activation is consistently found in patients. In this report, a patient without digestive tract disease is described, who experienced complete remission of rosacea symptoms following ingestion of a material intended to sweep through the digestive tract and reduce transit time below 30 h. It is possible that intestinal bacteria are capable of plasma kallikrein-kinin activation and that flushing symptoms and the development of other characteristic features of rosacea result from frequent episodes of neurogenic inflammation caused by bradykinin-induced hypersensitization of facial afferent neurones. The possible relevance of this hypothesis to other conditions featuring afferent hypersensitivity, such as fibromyalgia, is considered.

show abstract

“…Inasmuch as some rosacea patients complain of vague gastrointestinal troubles, several functional and morphological investigations on the func tion and morphology of the stomach and small bowel have been carried out, but with inconclusive and contradictory results [Brown, 1925;Eastwood, 1928;Usher, 1941;Fry and Swann, 1968;Marks and Shuster, 1970].…”

mentioning

confidence: 99%

Pancreatic Exocrine Function in Rosacea

Barba¹,

Rosa

Angelini

et al. 1982

Dermatology

View full text Add to dashboard Cite

As some rosacea patients complain of gastrointestinal troubles and the administration of pancreatic extracts ameliorates both dyspepsia and skin lesions, the pancreatic exocrine function in 21 subjects affected with rosacea has been investigated by means of the secretin-cerulein infusion test. 21 healthy controls have been studied for comparison. No difference was found between rosacea and control subjects for flow rate, bicarbonate and chymotrypsin concentration and output, while lipase concentration and output was significantly lower in rosacea patients, with a decrease ranging from 18.5 to 66% of normal values. Therefore, a deficient lipase secretion could be responsible, at least partly, for the clinical manifestations of rosacea.

show abstract

Gastroscopic Observations in Rosacea

Cited by 13 publications

References 2 publications

Abo Blood Groups and Skin Diseases.

Abo Blood Groups and Skin Diseases.

Remission of rosacea induced by reduction of gut transit time

Pancreatic Exocrine Function in Rosacea

Contact Info

Product

Resources

About