Gastroschisis: a systematic review of diagnosis, prognosis and treatment

Ferreira, Rafael Batista; Mendonça, Carolina Rodrigues; Ramos, Lelia Luanne Gonçalves; Tacon, Fernanda Sardinha de Abreu; Amaral, Waldemar Naves do; Ruano, Rodrigo

doi:10.1080/14767058.2021.1909563

Cited by 16 publications

(30 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In any case, the significant increase (p = 0.000) of the antenatal diagnosis rate led in our country to the significant increase of the number of births by cesarean section and implicitly to the decrease of GA, as observed in Table 1. The birth rate by cesarean section in the last decade in our country is similar to that reported by other recent studies conducted in developed countries, i.e., 50 versus 55% [13].…”

Section: Discussionsupporting

confidence: 91%

“…There has been a lot of controversy about GA at delivery. Some studies suggest that elective earlier delivery anticipation may reduce intestinal damage and enhance neonatal outcome [13]; this could not be demonstrated in our study. We must not lose sight of the fact that the decrease of GA implicitly leads to the decrease of BW, the latter factor being directly correlated with an unfavorable evolution and increasing by 4.90 times the risk of death in our study.…”

Section: Discussioncontrasting

confidence: 77%

See 1 more Smart Citation

Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis

Ţarcă

Roşu

Cojocaru

et al. 2021

JPM

View full text Add to dashboard Cite

Gastroschisis is a congenital abdominal wall defect that presents an increasing occurrence at great cost for the health system. The aim of the study is to detect the main factors of an unfavorable evolution in the case of gastroschisis and to find the best predictors of death. Methods: we conducted a retrospective cohort study of neonates with gastroschisis treated in a tertiary pediatric center during the last 30 years; 159 patients were eligible for the study. Logistic regression was used to determine the risk of death, estimated based on independent variables previously validated by the chi-square test. Results: if the birth weight is below normal, then we find an increased risk (4.908 times) of evolution to death. Similarly, the risk of death is 7.782 times higher in the case of developing abdominal compartment syndrome, about 3 times in the case of sepsis and 7.883 times in the case of bronchopneumonia. All four independent variables contributed 47.6% to the risk of death. Conclusion: although in the past 30 years in our country we have seen transformational improvements in outcome of gastroschisis, survival rates increasing from 26% to 52%, some factors may still be ameliorated for a better outcome.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussioncontrasting

confidence: 77%

Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis

Ţarcă

Roşu

Cojocaru

et al. 2021

JPM

View full text Add to dashboard Cite

show abstract

“…The overall postnatal survival rate of neonates with gastroschisis is more than 90%. 96,97 However, the condition is associated with significant morbidities that may result from the primary disease or the surgical procedure, including sepsis, necrotizing enterocolitis, short bowel syndrome, intestinal atresia, bowel obstruction, and volvulus which influenced the neonate's final prognosis. 97,98 Complex gastroschisis is associated with increased, up to 7-fold, in-hospital mortality as compared to simple gastroschisis.…”

Section: Prognosismentioning

confidence: 99%

“…96,97 However, the condition is associated with significant morbidities that may result from the primary disease or the surgical procedure, including sepsis, necrotizing enterocolitis, short bowel syndrome, intestinal atresia, bowel obstruction, and volvulus which influenced the neonate's final prognosis. 97,98 Complex gastroschisis is associated with increased, up to 7-fold, in-hospital mortality as compared to simple gastroschisis. 99,100 The presence of a higher incidence of cardiac and pulmonary comorbidities in neonates with complex gastroschisis in the presence of other comorbidities may also contribute to the poorer outcome for complex patients.…”

Section: Prognosismentioning

confidence: 99%

Gastroschisis: Anatomic Defects, Etiopathogenesis, Treatment, and Prognosis

Maheshwari¹,

Rahman²,

Kasniya³

et al. 2022

Newborn

View full text Add to dashboard Cite

Gastroschisis is a congenital defect in the abdominal wall that is typically located to the right of the umbilicus. The intestines, and sometimes parts of the liver and the stomach, also protrude into the amniotic space. Unlike in omphaloceles, these visceral organs do not have a covering sac and are directly exposed to the amniotic fluid. The organs show variable degrees of inflammatory changes and scarring. In this review, we have summarized currently available information on the anatomical changes in the intestine directly exposed to the amniotic fluid, the etiopathogenesis, treatment, and prognosis.

show abstract

“…Herniated viscera, including small and large bowel, liver, spleen, and bladder, are at a risk of stenosis or atresia, leading to further complications, including volvulus, vascular insufficiency, and necrosis [10,12,13]. Gastroschisis is most commonly located to the right of the intact umbilical cord and affects 0.045% of live births [10,12,14]. Hypotheses regarding pathogenesis of gastroschisis include teratogenic exposure, delayed umbilical ring closure during physiologic herniation, and right umbilical vein looping and strangulation of the bowels preventing development and/or return of viscera [15].…”

Section: Introductionmentioning

confidence: 99%

An Unusual Combination of Arthrogryposis, Gastroschisis, Cecal Volvulus, and Malignant Hyperthermia in a Young Woman: A Case Report

et al. 2022

View full text Add to dashboard Cite

Rare coexistence of disease or pathology Background:The purpose of this study is to discuss a patient with a history of conditions, including arthrogryposis, gastroschisis, and malignant hyperthermia, who presented with cecal volvulus requiring urgent surgical intervention. Case Report:A 29-year-old woman with a history of arthrogryposis, gastroschisis, malignant hyperthermia, and multiple childhood abdominal surgeries presents to the Emergency Department (ED) with 2 days of abdominal pain and bloody diarrhea. A CT abdomen/pelvis revealed findings concerning for a cecal volvulus. The patient was premedicated and monitored closely by the anesthesia team due to her history of malignant hyperthermia. She underwent an exploratory laparotomy, where a dilated cecum and proximal ascending colon were found to be completely volvulized around the mesentery. Manual bowel detorsion was performed, which resulted in reperfusion of the ischemic-appearing bowel, which then appeared viable. She recovered well after the procedure and was discharged on postoperative day 5. Conclusions:This case highlights a patient who presented with a combination of 4 findings: arthrogryposis, gastroschisis, malignant hyperthermia, and cecal volvulus. With arthrogryposis reported to be associated with gastroschisis and malignant hyperthermia, this report not only corroborates this association, but also aims to draw attention to the fact that these conditions have potential to occur jointly with cecal volvulus. Given the patient's history of gastroschisis requiring extensive abdominal surgeries that contribute as risk factors for cecal volvulus, it is possible there may be other arthrogryposis patients who present with cecal volvulus similar to that seen in this patient.

show abstract

Gastroschisis: a systematic review of diagnosis, prognosis and treatment

Cited by 16 publications

References 60 publications

Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis

Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis

Gastroschisis: Anatomic Defects, Etiopathogenesis, Treatment, and Prognosis

An Unusual Combination of Arthrogryposis, Gastroschisis, Cecal Volvulus, and Malignant Hyperthermia in a Young Woman: A Case Report

Contact Info

Product

Resources

About