Gastroretentive Drug Delivery Systems: A Summarized Overview.
Ahmed Tafish,
Amira Ebraheem,
Eman El Naggar
et al.
Abstract:Gastric emptying is a complicated process, thus the in vivo performance of drug delivery systems is unknown. Many physiological obstacles including; short gastric residency time (GRT) and variable gastric emptying time (GET), have reduced the efficacy of oral dosage forms. To combat this fickleness, attempts have been undertaken to increase the dosage form's retention time, resulting in the creation of Gastroretentive Drug Delivery Systems (GRDDS). The GRDDS can stay in the stomach for an extended period of ti… Show more
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