Gastrointestinal tumors in children and adolescents

Rectal adenocarcinoma following cranio-spinal radiotherapy for cerebellar medulloblastoma

“…Increased survival rates in children treated with radiotherapy for primary childhood malignancies means that the risk of developing second cancers whilst still in childhood is also increased; these second childhood malignancies are predominantly leukaemias and lung cancers [2]. Rectal adenocarcinoma is extremely rare in children [3], however the relative risk for developing colorectal cancer has been shown to be significantly raised following chemotherapy following treatment for nonHodgkin's lymphoma [1]. In one case series of 429 patients treated with radiotherapy for childhood solid tumours, 13 (3%) developed a second malignant neoplasm, of which one was reported as a colon cancer [4].…”

Metastatic Liver Disease: Colorectal Carcinomas

“…Parts of the tumors are classical adenocarcinomas of the colorectal type, but mucinous or colloid carcinoma (Buchman and Calhoun 1958;Tandon et al 1985;Brown et al 1992;Redkar et al 1993;Malik and Kamath 2011) and signet ring-cell carcinoma (Takai et al 1988;Pandey et al 2008) also occur, the mucinous variant being particularly common in several studies, amounting to 50 % (Hoerner 1958; Ladd and Grosfeld 2006). In adolescents, the tumor was a poorly differentiated adenocarcinoma in the majority of cases (Odone et al 1982).…”

Lymphomas in childhood

“…Olguların az bir kıs-mında portal alana yerleşmiş lenfadenopatiye bağlı sarılık gelişebilir (20) . Salt mide lenfoması çocukluk çağında ender görülmektedir (21) . Diğer ender tutulum alanları böbrekler, overler ve testislerdir (1) .…”