Gastrointestinal stromal tumour of the stomach showing lymph node metastases

Laparoscopic gastric resection for gastrointestinal stromal tumors

“…In addition, patients with active gastrointestinal hemorrhage are approached urgently via laparotomy because of potential hemodynamic alterations from pneumoperitoneum. Likewise, the rare (\5%) GIST with lymph node metastasis frequently determined by preoperative endoscopic ultrasound and fine-needle aspiration is managed in a manner similar to a gastric adenocarcinoma [18].…”

Lymph node metastasis in gastrointestinal stromal tumours (GIST) occurs preferentially in young patients ≤40 years: an overview based on our case material and the literature

“…Accordingly, nodal dissection is generally not recommended for GIST treatment [3][4][5]. Nevertheless, scattered case reports on GIST metastasising to lymph nodes are encountered in the recent literature [8][9][10][11][12]. However, we are not aware of any report analysing in details the clinicopathological characteristics of these rare GISTs giving rise to nodal metastasis.…”

Gastric gastrointestinal stromal tumor with synchronous metastasis to the esophagus: case report and review of the literature

“…Lymphogenous metastasis of GIST is very rare [13], and, in this case, the esophageal tumor had no lymphatic structures observed microscopically. A few microscopic nests of tumor cells were observed in the subserosal layer between the tumors, but these tumor cells had no intravascular involvement.…”

“…GISTs are considered malignant, with metastases that occur mainly via the hematogenous route, whereas lymphogenous metastasis are quite rare [13]. Mutational analysis of the c-kit gene in GISTs is essential for the accurate diagnosis of GISTs and also to predict effi cacy for molecular targeting of drug therapy in patients with recurrent disease.…”