Gastrointestinal-specific anxiety: an important factor for severity of GI symptoms and quality of life in IBS

Jerndal, Per; Ringström, Gisela; Agerforz, Pia; Karpefors, Martin; Akkermans, L.M.A.; Bayati, A.; Simrén, Magnus

doi:10.1111/j.1365-2982.2010.01493.x

Cited by 151 publications

(158 citation statements)

References 49 publications

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“…Anxiety, depression, and somatization are more prevalent in IBS patients. Jerndal et al (2010) found that anxiety, which is an important mediating factor, greatly affects the severity of symptoms and QOL, and that reduction of anxiety can achieve a general improvement in IBS symptoms. Two recent studies concluded that depression and somatization were independently associated with IBS (Nicholl et al, 2008;Savas et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

Liu

Xiao

Yao

2014

J. Zhejiang Univ. Sci. B

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Abstract:The prevalence of irritable bowel syndrome (IBS) and associated factors, especially psychological and lifestyle factors, in nurses in China have not been investigated previously. The aims of this study were to assess the prevalence of IBS in nurses, to evaluate whether factors, such as psychological disorders, are associated with IBS, and to determine whether psychological disorders can influence the severity of symptoms of IBS and quality of life (QOL). A cross-sectional study was conducted for Chinese nurses from November 2012 to February 2013. Participants were asked to complete questionnaires. The prevalence of IBS was 17.4%. The revised symptom checklist 90 (SCL-90-R) scores were significantly higher for nurses with IBS than for those without IBS (P<0.001), and no difference in scores between IBS subtypes was found (F=1.893, P=0.142). The scores of QOL for nurses with and without IBS were 77.18±21.93 and 88.44±11.89 (P<0.001), respectively. Psychological disorders did not show statistically significant correlations with severity of symptoms of IBS or QOL. Alcohol consumption, low level of exercise, and psychological disorders were risk factors for IBS. In summary, nurses in China show a high prevalence of IBS. Psychological disorders and some related lifestyle factors are probably responsible for the development of IBS in nurses.

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Section: Introductionmentioning

confidence: 99%

A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

Liu

Xiao

Yao

2014

J. Zhejiang Univ. Sci. B

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“…[13][14][15][16][17] Previously, it has been reported that nursing professionals who participate in a rotating shift schedule are at a higher risk of psychosocial problems than are those who work the day shift. 18 However, the role of psychosocial risk in shift-working professionals in the development of FGIDs remains obscure.…”

Section: Discussionmentioning

confidence: 99%

Psychosocial Stress in Nurses With Shift Work Schedule Is Associated With Functional Gastrointestinal Disorders

Koh¹,

Kim²,

Oh³

et al. 2014

J Neurogastroenterol Motil

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Background/Aims The aim of this study was to investigate the role of psychosocial problems and their associations with rotating shift work in the development of functional gastrointestinal disorders. Methods In this cross-sectional observation study, survey was administered to nurses and nurse assistants in a referral hospital. In addition to demographic questions, subjects were asked to complete the Rome III Questionnaire, Pittsburgh Sleep Quality Index and Rome III Psychosocial Alarm Questionnaire. Results Responses from 301 subjects were assessed. The overall prevalence of irritable bowel syndrome (IBS) and functional dyspepsia (FD) were 15.0% and 19.6%, respectively. Psychosocial alarms were prevalent in the nursing personnel (74.8% with alarm presence and 23.3% with serious condition) and were more frequent among rotating shift workers (84.7% vs. 74.5% for alarm presence and 28.1% vs. 13.3% for serious condition). The prevalence of both IBS and FD significantly increased with psychosocial risk. An independent risk factor for IBS was serious psychosocial alarm (adjusted odds ratio [aOR], 10.75; 95% confidence interval (CI), 1.30–88.99; P = 0.028). Serious psychosocial alarm was an independent risk factor for FD (aOR, 7.84; 95% CI, 1.98–31.02; P = 0.003). Marriage (aOR 0.30; 95% CI, 0.09–0.93; P = 0.037) was associated with the decreased risk of FD. Conclusions The high prevalence of psychosocial stress among nurses who work rotating shifts is associated with the development of functional gastrointestinal disorders.

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“…[10][11][12][13][15][16][17][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] The baseline characteristics of included studies are shown in Table 1 22,29 Sphere score in 1 study, 24 and the Beck Anxiety Inventory (BAI) in 1 study. 30 …”

Section: Baseline Characteristics Of Included Studiesmentioning

confidence: 99%

“…2B). 11,13,22,25,28,29,34,36 However, 4 of 8 outlier studies were age-sex (hyphen) unmatched. 13,28,29,34 The Anxiety Level in Irritable Bowel Syndrome Patients…”

Section: The Depression Level In Irritable Bowel Syndrome Patientsmentioning

confidence: 99%

The Increased Level of Depression and Anxiety in Irritable Bowel Syndrome Patients Compared with Healthy Controls: Systematic Review and Meta-analysis

Lee

Doo

Choi

et al. 2017

J Neurogastroenterol Motil

172

151

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Background/AimsIrritable bowel syndrome (IBS) patients commonly experience psychiatric disorders, such as depression and anxiety. This meta-analysis sought to compare depression and anxiety levels between IBS patients and healthy controls. MethodsWe searched major electronic databases (PubMed, EMBASE, MEDLINE, and Cochrane library) to find comparative studies on IBS patients and healthy controls. The primary outcome was a standardized mean difference (SMD) of anxiety and depression levels; subgroup analyses were conducted according to IBS-subtypes. ResultsIn total, 2293 IBS patients and 4951 healthy controls from 27 studies were included. In random effect analysis, depression and anxiety levels were significantly higher in IBS patients (pooled SMD = 0.76; 95% CI, 0.62-0.90; P < 0.001; I 2 = 77.2% and pooled SMD = 0.84; 95% CI, 0.67-1.01; P < 0.001; I 2 = 85.6%, respectively). Both analyses' funnel plots showed symmetry. In meta-regression analysis, heterogeneity was due to the studied region and questionnaire type for both depression and anxiety. In sub-group analyses of IBS-subtype, the pooled SMDs of depression and anxiety levels (IBS with predominant constipation: 0.83 and 0.81, IBS with predominant diarrhea: 0.73 and 0.65, and IBS with mixed bowel habits: 0.62 and 0.75; P < 0.001, respectively) were significantly higher in all IBS-subtypes. ConclusionsThe present meta-analysis showed depression and anxiety levels to be higher in IBS patients than in healthy controls, regardless of IBSsubtype. However, the gender effect on psychological factors among IBS patients could not be determined and should be evaluated in prospective studies.

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Gastrointestinal-specific anxiety: an important factor for severity of GI symptoms and quality of life in IBS

Abstract: Gastrointestinal-specific anxiety seems to be an important factor for GI symptom severity and QOL in patients with IBS.

Cited by 151 publications

References 49 publications

A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

Psychosocial Stress in Nurses With Shift Work Schedule Is Associated With Functional Gastrointestinal Disorders

The Increased Level of Depression and Anxiety in Irritable Bowel Syndrome Patients Compared with Healthy Controls: Systematic Review and Meta-analysis

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