Gastrointestinal Origins of Pyogenic Liver Abscess

Jolobe, Oscar M.P.

doi:10.1016/j.amjmed.2019.10.011

Cited by 1 publication

(1 citation statement)

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“…In a previous report, a liver abscess associated with K. pneumoniae was related to a gastrointestinal tumor. 12 In addition, inflammation caused by bile duct stones is one source of a liver abscess. 13 These conditions may result in PLA.…”

Section: Discussionmentioning

confidence: 99%

Pyogenic liver abscess caused by extended-spectrum β-lactamase-producing hypervirulent Klebsiella pneumoniae diagnosed by third-generation sequencing: a case report and literature review

Zhang,

Huang,

et al. 2023

J Int Med Res

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We report a case of a woman with diabetes mellitus and choledocholithiasis who had a low fever with chills and severe weakness for 7 days. The patient’s abdominal tenderness was positive. Computed tomography and magnetic resonance imaging showed a giant abscess in the liver. The production of extended-spectrum β-lactamases by hypervirulent Klebsiella pneumoniae was found in the purulent fluid of the liver by nanopore-based metagenomic third-generation sequencing combined with an antibiotic susceptibility test. The patient recovered after intravenous antibiotic therapy and percutaneous drainage. Patients with a history of diabetes mellitus and choledocholithiasis should be aware of the possibility of pyogenic liver abscesses caused by hypervirulent Klebsiella pneumoniae. To rapidly control the development of this disease, nanopore-based metagenomic third-generation sequencing plays an important role not only in rapidly identifying pathogens, but also in guiding the use of antibiotics.

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Section: Discussionmentioning

confidence: 99%