Gastrointestinal Manifestation and Bipolar Disorder: About a Clinical Case

Abstract

Introduction: The frequency of gastrointestinal manifestations in patients suffering with mood disorders, particularly bipolar disorders, pose specific physiopathological, etiological and therapeutic questions. We propose to address this issue through this clinical case. Clinical Case: We report here the case of a female patient 29-year-old, followed in psychiatry since 2014 for bipolar disorder type I and presenting an irritable colon syndrome, a biliary cyst, gastric diverticula and a chronic constipation. Discussion: Several hypotheses on the links between affectivity and gastrointestinal functioning are discussed in the light of the literature, explaining the role of the brain-gut axis as well as the involvement of the receptological profile of neuroleptics and also the role of the iatrogenicity of psychotropic drugs. Conclusion: There are definite links between affectivity and gastrointestinal manifestations. A better understanding of these links could enlighten us on the etiopathogeny of mood disorders, especially bipolar disorders, in order to guarantee a better management of psychiatric pathology as well as gastrointestinal manifestations.