Gastrointestinal: Esophagitis caused by alendronate

Kk, Sia; Iser, David; Heng, R; Ry, Chen

doi:10.1111/j.1440-1746.2004.03570.x

Cited by 3 publications

(2 citation statements)

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“…B. durch heiße Getränke und Speisen [12] Infektionen ▶ z. B. Herpes-simplex-Ösophagitis [13] Medikamente ▶ Alendronat [14] ▶ Imatinib [15] ▶ Sunitinib [16] eosinophile Ösophagitis ▶ akzidentelle Ablösung einer vulnerablen Schleimhaut durch die diagnostische Endoskopie [17] Transplantationen ▶ Graft-versus-Host-Disease ▶ nach allogener Stammzelltransplantation (SZT) [18] ▶ nach autologer peripherer SZT [19] Morbus Behçet …”

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Exfoliative Ösophagitis unter Dabigatran

Scheppach¹,

Meesmann

2015

Dtsch med Wochenschr

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History | A 77-year-old woman was admitted with severe chest pain, heartburn, dysphagia and odynophagia. She had been on dabigatran for 13 months due to atrial fibrillation and arterial hypertension. Investigations and findings | Endoscopy of the esophagus revealed sloughing of mucosal casts, predominantly in the upper half of the organ. Treatment and course | The patient was placed on pantoprazol, local anaesthetic antacid and i. v. fluids. Dabigatran was discontinued. The symptoms disappeared within 3 days. Control endoscopy after 12 days showed complete healing of the esophageal mucosa. Conclusion | The intake of dabigatran was associated with exfoliative esophagitis, possibly due to caustic tissue damage by prolonged drug contact.

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Exfoliative Ösophagitis unter Dabigatran

Scheppach¹,

Meesmann

2015

Dtsch med Wochenschr

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“…The bisphosphonates (alendronate, risedronate, ibandronate), can cause erosion of the esophageal lining (Sia, Iser, Heng & Chen, 2004). Parathyroid hormone, ("PTH"; teriparatide) although an anabolic, rather than simply anticatabolic, treatment, requires daily injections and cannot be used for more than two years.…”

Section: B Treatment Of Bone Diseasesmentioning

confidence: 99%

I. Studies of cyclic peptides containing the arginine-glycine-aspartic acid pharmacophore; II. Targeting drugs to bone.

Richter¹

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Current awareness: Pharmacoepidemiology and drug safety

2004

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 20 sections: 1 Books, Reviews & Symposia; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Gastrointestinal: Esophagitis caused by alendronate

Cited by 3 publications

References 0 publications

Exfoliative Ösophagitis unter Dabigatran

Exfoliative Ösophagitis unter Dabigatran

I. Studies of cyclic peptides containing the arginine-glycine-aspartic acid pharmacophore; II. Targeting drugs to bone.

Current awareness: Pharmacoepidemiology and drug safety

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