Abstract:About 2 percent of developed countries population use vitamin K antagonists (VKA), such as warfarin. These anticoagulation drugs are commonly prescribed for the purpose of thromboembolism prevention, in cases of atrial fibrillation, mechanical heart valves, deep vein thrombosis, pulmonary embolism and etc. The frequency of VKA prescription is massively increasing in the whole world. The main reason for it is the ageing of the population. As the usage of anticoagulants is increasing, doctors more often get to e… Show more
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