2021
DOI: 10.1590/s0004-2803.202100000-77
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Gastroesophageal Reflux Disease in Infants Who Presented Brief Resolved Unexplained Event (Brue)

Abstract: BACKGROUND: The term brief resolved unexplained events (BRUE) is a description of the acute event occurring in infants less than 1-year-old that includes at least one of the following characteristics: cyanosis or pallor; absent, decreased, or irregular breathing; marked change in tone or altered level of responsiveness. An investigative proceeding is required to identify the triggering phenomenon in those who are at high risk of complications. Prolonged esophageal pHmetry has been used as a tool in searching … Show more

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Cited by 1 publication
(2 citation statements)
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References 22 publications
(27 reference statements)
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“…The 24-hour esophageal multichannel intraluminal impedance-pH monitoring is considered to be more suitable for diagnose GERD by correlating symptoms with acid and non-acid GER events (1). In this study, the overall abnormal rate of MII-pH monitoring was 39.2%, which is consistent with previous studies in infants (14)(15)(16). Esophageal symptom presented infants appear to have higher abnormal rate of MII-pH monitoring as in this study (11,17).…”
Section: Discussionsupporting
confidence: 93%
See 1 more Smart Citation
“…The 24-hour esophageal multichannel intraluminal impedance-pH monitoring is considered to be more suitable for diagnose GERD by correlating symptoms with acid and non-acid GER events (1). In this study, the overall abnormal rate of MII-pH monitoring was 39.2%, which is consistent with previous studies in infants (14)(15)(16). Esophageal symptom presented infants appear to have higher abnormal rate of MII-pH monitoring as in this study (11,17).…”
Section: Discussionsupporting
confidence: 93%
“…Infants with comorbidities display more extra-esophageal symptoms such as life-threatening events (15,18) or upper airway involvement (19), which are di cult to differentiate GERD from their underlying conditions and commonly refer for 24-hour MII-pH survey. However, in this study, infants with extra-esophageal symptom appeared to have lower abnormal rates of MII-pH monitoring than those infants with esophageal symptom.…”
Section: Discussionmentioning
confidence: 99%